Cucurbitacins from Bacopa monnieri

被引:46
作者
Bhandari, Pamita [1 ]
Kumar, Neeraj [1 ]
Singh, Bikram [1 ]
Kaul, Vijay K. [1 ]
机构
[1] Inst Himalayan Bioresource Technol, Nat Plant Prod Div, Palampur 176061, HP, India
关键词
Bacopa monnieri; Scrophulariaceae; cucurbitacins; bacobitacin A-D; ESI-QTOF-MS;
D O I
10.1016/j.phytochem.2007.03.013
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Four cucurbitacins, bacobitacin A-D (1-4) as well as, a known cytotoxic, cucurbitacin E (5) together with three known phenylethanoid glycosides, monnieraside I, III and plantioside B were isolated form the aerial part of Bacopa monnieri. Their structures were elucidated on the basis of extensive spectroscopic investigations (1D, 2D NMR and ESI-QTOF-MS/MS). This is the first report on the characterization of cucurbitacins in B. monnieri. (c) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1248 / 1254
页数:7
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