An integrin chicken and egg problem: which comes first, the extracellular matrix or the cytoskeleton?

被引：7

作者：

Brown, NH

机构：

[1] Univ Cambridge, Wellcome CRC Inst, Cambridge CB2 1QR, England

[2] Univ Cambridge, Dept Anat, Cambridge CB2 1QR, England

来源：

CURRENT OPINION IN CELL BIOLOGY | 2000年 / 12卷 / 05期

关键词：

D O I：

10.1016/S0955-0674(00)00142-3

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Integrins have the ability to organise macromolecular structures both inside and outside the cell. Analysis of integrin function in the developing embryos of worms and flies suggests that, although the extracellular matrix directs integrins to organise intracellular proteins, the cytoskeleton may have the first word.

引用

页码：629 / 633

页数：5

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