Bioavailability of Various Polyphenols from a Diet Containing Moderate Amounts of Berries

被引:72
作者
Koli, Raika [1 ]
Erlund, Iris [1 ]
Jula, Antti [2 ]
Marniemi, Jukka [2 ]
Mattila, Pirjo [3 ]
Alfthan, Georg [1 ]
机构
[1] Natl Inst Hlth & Welf THL, Dis Risk Unit, Dept Chron Dis Prevent, FI-00300 Helsinki, Finland
[2] Natl Inst Hlth & Welf THL, Populat Studies Unit, Dept Chron Dis Prevent, FI-20720 Turku, Finland
[3] Agrifood Res Finland, FI-31600 Jokioinen, Finland
关键词
Berries; polyphenols; bioavailability; human; dietary intervention; PHENOLIC-ACIDS; MICROBIAL FERMENTATION; PLATELET-AGGREGATION; CHLOROGENIC ACID; BLOOD-PRESSURE; ELDERLY WOMEN; FOOD SOURCES; DIODE-ARRAY; RED WINE; ANTHOCYANINS;
D O I
10.1021/jf9024823
中图分类号
S [农业科学];
学科分类号
09 ;
摘要
Berries are a rich source of various polyphenols. The objective of this study was to investigate the bioavailability of polyphenols from berries. Middle-aged subjects (n = 72) consumed moderate amounts of berry or control products for 8 weeks in a randomized, placebo-controlled dietary intervention trial. Average intake of berries was 160 g/day (bilberries, lingonberries, black currants, and chokeberries). Plasma and urine polyphenols were analyzed by GC-MS and HPLC and berry polyphenols by HPLC. The total intake of polyphenols was 837 mg/day. Plasma quercetin, p-coumaric acid, 3-hydroxyphenylacetic acid, caffeic acid, protocatechuic acid, vanillic acid, homovanillic acid, and 3-(3-hydroxyphenyl)propionic acid increased significantly from the baseline in the berry group compared to the control group (p < 0.05). The urinary excretion of quercetin, p-coumaric acid, and 3-hydroxyphenylacetic acid increased significantly in the berry group compared to the control group (p < 0.05). In conclusion, a number of polyphenols are bioavailable from a diet containing moderate amounts of blue and red berries.
引用
收藏
页码:3927 / 3932
页数:6
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