Right heart function during acute respiratory distress syndrome

被引：44

作者：

Repesse, Xavier ^{[1
]}

Vieillard-Baron, Antoine ^{[1
,2
,3
]}

机构：

[1] Univ Hosp Ambroise Pare, Assistance Publ Hop Paris, Intens Care Unit, Sect Thorax Vasc Dis Abdomen Metab, F-92100 Boulogne, France

[2] Univ Versailles St Quentin Yvelines, Fac Med Paris Ile de France Ouest, F-78280 St Quentin En Yvelines, France

[3] UVSQ, INSERM U1018, CESP, Team EpReC Renal & Cardiovasc Epidemiol 5, F-94807 Villejuif, France

来源：

ANNALS OF TRANSLATIONAL MEDICINE | 2017年 / 5卷 / 14期

关键词：

Acute respiratory distress syndrome (ARDS); right ventricle (RV); acute cor pulmonale (ACP); driving pressure; hypercapnia; oxygenation; PRESSURE-LIMITED VENTILATION; INTENSIVE-CARE UNITS; ACUTE COR-PULMONALE; PERMISSIVE HYPERCAPNIA; PRONE POSITION; LOW-VOLUME; LUNG; MORTALITY; HYPERTENSION; PATHOPHYSIOLOGY;

D O I：

10.21037/atm.2017.06.66

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Acute respiratory distress syndrome (ARDS) is burdened with significant mortality, mainly in connection with circulatory failure. The right ventricle (RV) is the weak link of hemodynamic stability among ARDS patients and its failure, also named "severe" acute cor pulmonale (ACP), is responsible for excess mortality. Driving pressure >= 18 cmH(2)O, PaCO2 >= 48 mmHg and PaO2/FiO(2) <150 mmHg are three preventable factors recently identified as independently associated with ACP, on which ventilator strategy designed to protect the RV has to focus. This is largely achieved by the use of early and extended sessions of prone positioning (PP) and by daily monitoring of the RV by echocardiography.

引用

页数：5

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