Executive summary of the Japan Osteoporosis Society Guide for the Use of Bone Turnover Markers in the Diagnosis and Treatment of Osteoporosis (2018 Edition)

被引：56

作者：

Nishizawa, Yoshiki ^{[1
]}

Miura, Masakazu ^{[2
]}

Ichimura, Shoichi ^{[3
]}

Inaba, Masaaki ^{[4
]}

Imanishi, Yasuo ^{[4
]}

Shiraki, Masataka ^{[5
]}

Takada, Junichi ^{[6
]}

Chaki, Osamu ^{[7
]}

Hagino, Hiroshi ^{[8
]}

Fukunaga, Masao ^{[9
]}

Fujiwara, Saeko ^{[10
]}

Miki, Takami ^{[11
]}

Yoshimura, Noriko ^{[12
]}

Ohta, Hiroaki ^{[13
]}

机构：

[1] Univ Publ Corp Osaka, Abeno Ku, 1-2-7 Asahi Machi, Osaka, Osaka 5450051, Japan

[2] Hokuriku Univ, Fac Pharmaceut Sci, Hlth Aging Res Grp, 3Ho Kanagawa Machi, Kanazawa, Ishikawa 9201181, Japan

[3] Kyorin Univ, Fac Med, Dept Orthopaed Surg, 6-20-2 Shinkawa, Mitaka, Tokyo 1818611, Japan

[4] Osaka City Univ, Grad Sch Med, Dept Metab Endocrinol & Mol Med, Abeno Ku, 1-4-3 Asahi Machi, Osaka, Osaka 5458585, Japan

[5] Res Inst & Practice Involut Dis, 1610-1 Meisel, Nagano 3998101, Japan

[6] Kitago Orthopaed Clin, Shiroishi Ku, 8-5-33 Kitago,3Jyo, Sapporo, Hokkaido 0030833, Japan

[7] Yokohama Rosai Hosp, Dept Obstet & Gynecol, Kohoku Ku, 3211 Kozukue Chou, Yokohama, Kanagawa 2220036, Japan

[8] Tottori Univ, Fac Med, Sch Hlth Sci, 86 Nishicho, Yonago, Tottori 6838503, Japan

[9] Kawasaki Med Sch, 577 Matushima, Kurashiki, Okayama 7010192, Japan

[10] Yasuda Womens Univ, Fac Pharm, Dept Pharm, Asaminami Ku, 6-13-1 Yasuhigashi, Hiroshima, Hiroshima 7310152, Japan

[11] Izumiotsu Municipal Hosp, 16-1 Gejochomachi, Izumiotsu, Osaka 9500027, Japan

[12] Univ Tokyo, Dept Prevent Med Locomot Organ Disorders, 22nd Century Med & Res Ctr, Bunkyo Ku, 7-3-1 Hongo, Tokyo 1138655, Japan

[13] Sanno Med Ctr, Womens Med Ctr, Minato Ku, 8-5-35 Akasaka, Tokyo 1070052, Japan

来源：

CLINICA CHIMICA ACTA | 2019年 / 498卷

关键词：

Guide; Bone turnover marker (BTM); Osteoporosis; Diagnosis; BIOCHEMICAL MARKERS; MINERAL DENSITY; WOMEN;

D O I：

10.1016/j.cca.2019.08.012

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

With the aging of society, the number of osteoporosis-related fractures is increasing. Prevention of osteoporosis and maintenance of the quality of life of osteoporosis patients require early diagnosis, effective treatment, and highly precise treatment monitoring. Although bone biopsy is clinically one of the essential techniques for diagnosis of osteoporosis, it is invasive and difficult to perform in general clinical practice. Bone mineral density measurement is another essential technique available in clinical practice that provides good precision. However, it is not effective for determining the appropriate treatment options or evaluating short-term treatment efficacy. On the other hand, bone turnover markers (BTMs) have gained attention because they provide information that is valuable for both the selection of treatment and short-term monitoring. BTMs are now positioned to become a tool for clinically assessing bone turnover outcomes. Since the Japan Osteoporosis Society issued its Guidelines for the Use of Bone Turnover Markers in the Diagnosis and Treatment of Osteoporosis in 2012, new drugs, drug formulations, and combination drug therapies have been approved; therefore, we updated the 2012 guidelines in the Guide for the Use of Bone Turnover Markers in the Diagnosis and Treatment of Osteoporosis (2018 Edition).

引用

页码：101 / 107

页数：7

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