In this paper, by means of constructing a special cone, we obtain a sufficient condition for the existence of positive solution for semipositone singular Sturm-Liouville boundary value problem on the half-line. The results obtained generalize and improve the corresponding results of Zhang and Liu in papers [X.G. Zhang, L.S. Liu, Positive solutions of superlinear semipositone singular Dirichlet boundary value problems, J. Math. Anal. Appl. 316 (2006) 525-537, Y.S. Liu, Existence and unboundedness of positive solutions for singular boundary value problems on half-line, Appl. Math. Comput. 144 (2003) 543-556]. (c) 2006 Elsevier Inc. All rights reserved.