Extended anticoagulation after venous thromboembolism: should it be done?

被引：12

作者：

Fernandes, Caio J. ^{[1
,2
,3
]}

Calderaro, Daniela ^{[1
,3
]}

Piloto, Bruna ^{[1
,3
]}

Hoette, Susana ^{[1
]}

Poyares Jardim, Carlos Vianna ^{[1
,3
]}

Souza, Rogerio ^{[1
,3
]}

机构：

[1] Univ Sao Paulo, Cardiopulm Dept, Heart Inst, Med Sch, 44 Av Dr Eneas Carvalho Aguiar, BR-05403000 Sao Paulo, SP, Brazil

[2] Univ Sao Paulo, Med Sch, Canc Inst, 251 Dr Arnaldo Ave, Sao Paulo, SP, Brazil

[3] Sirio Libanes Hosp, 115 Adma Jafet St, Sao Paulo, SP, Brazil

来源：

THERAPEUTIC ADVANCES IN RESPIRATORY DISEASE | 2019年 / 13卷

关键词：

deep vein thrombosis; direct oral anticoagulants; extended anticoagulation; provoked; pulmonary embolism; treatment; unprovoked; venous thromboembolism; INTENSITY WARFARIN THERAPY; DEEP-VEIN THROMBOSIS; PULMONARY-EMBOLISM; SECONDARY PREVENTION; 1ST EPISODE; LONG-TERM; RISK; ASPIRIN; CANCER; RECURRENCE;

D O I：

10.1177/1753466619878556

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Most physicians understand venous thromboembolism (VTE) to be an acute and time-limited disease. However, pathophysiological and epidemiological data suggest that in most patients VTE recurrence risk is not resolved after the first 6 months of anticoagulation. Recurrence rates are high and potentially life-threatening. In these cases, it would make sense to prolong anticoagulation for an undetermined length of time. However, what about the bleeding rates, induced by prolonged anticoagulation? Would they not outweigh the benefit of reducing the VTE recurrent risk? How long should anticoagulation be continued, and should all patients suffering from VTE be provided with extended anticoagulation? This review will address the most recent data concerning extended anticoagulation in VTE secondary prophylaxis. The reviews of this paper are available via the supplementary material section.

引用

页数：13

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