The relation between Chlamydia pneumoniae infection and abdominal aortic aneurysm:: Case-control study

被引：22
作者：
Blanchard, JF
Armenian, HK
Peeling, R
Friesen, PP
Shen, CX
Brunham, RC
机构：
[1] Univ Manitoba, Dept Community Hlth Sci, Fac Med, Winnipeg, MB R3E 0W3, Canada
[2] Univ Manitoba, Dept Med Microbiol, Fac Med, Winnipeg, MB R3E 0W3, Canada
[3] Lab Ctr Dis Control, Natl Lab STDs, Winnipeg, MB, Canada
[4] Hlth Sci Ctr, Winnipeg, MB, Canada
[5] British Columbia Ctr Dis Control, Vancouver, BC, Canada
[6] Johns Hopkins Univ, Sch Hyg & Publ Hlth, Dept Epidemiol, Baltimore, MD USA
来源：
CLINICAL INFECTIOUS DISEASES | 2000年 / 30卷 / 06期
基金：
英国医学研究理事会;
关键词：
D O I：
10.1086/313806
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Due to recent interest in the role of Chlamydia pneumoniae as a pathogen of the vascular system, a case-control study was conducted to investigate the association between serological evidence of infection with C. pneumoniae and the occurrence of abdominal aortic aneurysm. Detectable IgG antibody to C. pneumoniae was more common among abdominal aortic aneurysm cases than among control patients (adjusted odds ratio, 5.97; P = .08), as was detectable IgM antibody (10% vs. 0%; P = .02). These findings suggest that infection with C. pneumoniae may play a role in the pathogenesis of abdominal aortic aneurysm; therefore, further research in this area is warranted.
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收藏
页码：946 / 947
页数：2
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