Pregnancy and the Patient with Inflammatory Bowel Disease Fertility, Treatment, Delivery, and Complications

被引:45
|
作者
McConnell, Ryan A. [1 ]
Mahadevan, Uma [2 ]
机构
[1] Univ Calif San Francisco, Div Gastroenterol, 1701 Divisadero St,120, San Francisco, CA 94115 USA
[2] UCSF Ctr Colitis & Crohns Dis, Div Gastroenterol, 1701 Divisadero St,120, San Francisco, CA 94115 USA
关键词
Inflammatory bowel disease; Crohn disease; Ulcerative colitis; Fertility; Pregnancy; Obstetric delivery; Breast feeding; Drug-related side effects and adverse reactions; POUCH-ANAL ANASTOMOSIS; IN-VITRO FERTILIZATION; ULCERATIVE-COLITIS; CROHNS-DISEASE; BIRTH OUTCOMES; TNF-ALPHA; PIANO REGISTRY; DANISH COHORT; UNITED-STATES; BREAST-MILK;
D O I
10.1016/j.gtc.2016.02.006
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
For many women with inflammatory bowel disease (IBD), the illness coincides with their childbearing years. IBD increases the risk of pregnancy complications and adverse pregnancy outcomes. The multidisciplinary care team should emphasize the importance of medication adherence to achieve preconception disease control and maintain corticosteroid-free remission throughout pregnancy. Medication adjustments to reduce fetal exposure may be considered on an individualized basis in quiescent disease; however, any benefits of such adjustments remain theoretic and there is risk of worsening disease activity. Mode of delivery is determined by obstetric indications, except for women with active perianal disease who should consider cesarean delivery.
引用
收藏
页码:285 / +
页数:18
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