Cooperativity between phenolic antioxidant- and Ah receptor-mediated induction of human UDP-glucuronosyltransferase (UGT1A6) expression

被引：0
|
作者：
Buckler, F [1 ]
Schmohl, S [1 ]
Schmiechen, A [1 ]
Bock, KW [1 ]
Schwarz, M [1 ]
Münzel, PA [1 ]
机构：
[1] Univ Tubingen, Dept Toxicol, D-72074 Tubingen, Germany
来源：
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY | 2003年 / 367卷
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
493
引用
收藏
页码：R127 / R127
页数：1
相关论文
共 50 条
  • [21] Expression of a functionally active human hepatic UDP-glucuronosyltransferase (UGT1A6) lacking the N-terminal signal sequence in the endoplasmic reticulum
    Ouzzine, M
    Magdalou, J
    Burchell, B
    Fournel-Gigleux, S
    FEBS LETTERS, 1999, 454 (03): : 187 - 191
  • [22] CHOLESTASIS AND FARNESOID X RECEPTOR-MEDIATED REGULATION OF THE HUMAN HEPATIC BILE ACID UDP-GLUCURONOSYLTRANSFERASE (UGT) 1A3 GENE
    Erichsen, Thomas J.
    Aehlen, Andre
    Ehmer, Ursula
    Lankisch, Tim O.
    Manns, Michael P.
    Strassburg, Christian P.
    HEPATOLOGY, 2008, 48 (04) : 1121A - 1122A
  • [23] Importance of histidine residues for the function of the human liver UDP-glucuronosyltransferase UGT1A6: Evidence for the catalytic role of histidine 370
    Ouzzine, M
    Antonio, L
    Burchell, B
    Netter, P
    Fournel-Gigleux, S
    Magdalou, J
    MOLECULAR PHARMACOLOGY, 2000, 58 (06) : 1609 - 1615
  • [24] Induction of human UDP-glucuronosyltransferase UGT1A1 by flavonoids-structural requirements
    Walle, UK
    Walle, T
    DRUG METABOLISM AND DISPOSITION, 2002, 30 (05) : 564 - 569
  • [25] UDP-glucuronosyltransferase (UGT1A1*28 and UGT1A6*2) polymorphisms in Caucasians and Asians:: relationships to serum bilirubin concentrations
    Lampe, JW
    Bigler, J
    Horner, NK
    Potter, JD
    PHARMACOGENETICS, 1999, 9 (03): : 341 - 349
  • [26] Regulation via nuclear receptor of the human UDP-glucuronosyltransferase (UGT) 1a3
    Erichsen, T. J.
    Lankisch, T. O.
    Ehmer, U.
    Gillman, T. C.
    Remmel, R. P.
    Manns, M. P.
    Strassburg, C. P.
    JOURNAL OF HEPATOLOGY, 2007, 46 : S149 - S149
  • [27] Tissue-specific 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible expression of human UDP-glucuronosyltransferase UGT1A6
    Munzel, PA
    Bookjans, G
    Mehner, G
    Lehmkoster, T
    Bock, KW
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1996, 335 (01) : 205 - 210
  • [28] Farnesoid A Receptor-Mediated Regulation and Modulation By Ursodeoxycholic Acid of the Human UDP-Glucuronosyltransferase 1A3
    Erichsen, Thomas J.
    Aehlen, Andre
    Ehrner, Ursula
    Lankisch, Tim O.
    Manns, Michael P.
    Strassburg, Christian P.
    GASTROENTEROLOGY, 2009, 136 (05) : A800 - A800
  • [29] Effect of Genetic Polymorphisms in UDP-Glucuronosyltransferase 1A6 (UGT1A6) on Acetylsalicylic Acid Metabolism in Healthy Female Volunteers
    van Oijen, Martijn G. H.
    Barthelemy, Christine
    Janssen, Marcel J. R.
    Joiris, Etienne
    Peters, Wilbert H. M.
    Laheij, Robert J. F.
    Smits, Paul
    Odou, Pascal
    Jansen, Jan B. M. J.
    PHARMACOLOGY, 2009, 83 (04) : 237 - 242
  • [30] The significance of amino acid residue Asp446 for enzymatic stability of rat UDP-glucuronosyltransferase UGT1A6
    Iwano, H
    Yokota, H
    Ohgiya, S
    Yuasa, A
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1999, 363 (01) : 116 - 120
12345