Validation of the Adult ADHD Investigator Symptom Rating Scale (AISRS)

被引：89

作者：

Spencer, Thomas J. ^{[1
]}

Adler, Lenard A. ^{[2
]}

Qiao, Meihua ^{[3
]}

Saylor, Keith E. ^{[4
]}

Brown, Thomas E. ^{[5
]}

Holdnack, James A. ^{[6
]}

Schuh, Kory J. ^{[3
]}

Trzepacz, Paula T. ^{[7
]}

Kelsey, Douglas K. ^{[3
]}

机构：

[1] Massachusetts Gen Hosp, Clin & Res Program Pediat Psychopharmacol, Boston, MA 02114 USA

[2] NYU, Sch Med, New York, NY USA

[3] Lilly USA LLC, Indianapolis, IN USA

[4] NeuroScience Inc, Herndon, VA USA

[5] Yale Univ, Sch Med, Hamden, CT USA

[6] Harcourt Assessment Inc, Bear, DE USA

[7] Lilly Res Labs, Indianapolis, IN USA

来源：

JOURNAL OF ATTENTION DISORDERS | 2010年 / 14卷 / 01期

关键词：

atomoxetine; clinical improvement; hyperactivity; attention deficit; ATTENTION-DEFICIT/HYPERACTIVITY DISORDER; VALIDITY; COEFFICIENT; RELIABILITY; ATOMOXETINE; CHILDREN; PLACEBO; VERSION; LIFE;

D O I：

10.1177/1087054709347435

中图分类号：

B844 [发展心理学（人类心理学）];

学科分类号：

040202 ;

摘要：

Objective: Validation of the Adult ADHD Investigator Symptom Rating Scale (AISRS) that measures aspects of ADHD in adults. Method: Psychometric properties of the AISRS total and AISRS subscales are analyzed and compared to the Conners' Adult Attention-Deficit/Hyperactivity Disorder Rating Scale-Investigator Rated: Screening Version (CAARS-Inv:SV) and the Clinical Global Impression-ADHD-Severity Scale using data from a placebo-controlled 6-month clinical trial of once-daily atomoxetine. Results: The AISRS has high internal consistency, good convergent, and discriminant validities; modest divergent validity; and small ceiling and floor effects (<= 1%). It correlates highly with the CAARS-Inv:SV. Factor analysis confirms 2 AISRS subscales, hyperactivity-impulsive scale and inattention. The AISRS total and AISRS subscales perform stably. All scales demonstrate responsiveness to change with medication. Conclusion: The AISRS and its subscales are robust, valid efficacy measures of ADHD symptoms in adult patients. Its anchored items and semistructured interview are advancements over existing scales. (J. of Att. Dis. 2010; 14(1) 57-68).

引用

页码：57 / 68

页数：12

共 31 条

[1]

Adler Lenard A, 2005, J Atten Disord, V8, P121, DOI 10.1177/1087054705277168

[2] Once-Daily Atomoxetine for Adult Attention-Deficit/Hyperactivity Disorder A 6-Month, Double-Blind Trial [J].

Adler, Lenard A. ;

Spencer, Thomas ;

Brown, Thomas E. ;

Holdnack, James ;

Saylor, Keith ;

Schuh, Kory ;

Trzepacz, Paula T. ;

Williams, David W. ;

Kelsey, Douglas .

JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, 2009, 29 (01) :44-50

[3]

Barkley RA, 2002, J CLIN PSYCHIAT, V63, P10

[4]

Barkley RA, 1996, PEDIATRICS, V98, P1089

[5] Functional impairments in adults with self-reports of diagnosed ADHD: A controlled study of 1001 adults in the community [J].

Biederman, J ;

Faraone, SV ;

Spencer, TJ ;

Mick, E ;

Monuteaux, MC ;

Aleardi, M .

JOURNAL OF CLINICAL PSYCHIATRY, 2006, 67 (04) :524-540

[6] A double-blind comparison of galantamine hydrogen bromide and placebo in adults with attention-deficit/hyperactivity disorder - A pilot study [J].

Biederman, J ;

Mick, E ;

Faraone, S ;

Hammerness, P ;

Surman, C ;

Harpold, T ;

Dougherty, M ;

Aleardi, M ;

Spencer, T .

JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, 2006, 26 (02) :163-166

[7] An open-label trial of OROS methylphenidate,in adults with late-onset ADHD [J].

Biederman, Joseph ;

Mick, Eric ;

Spencer, Thomas ;

Surman, Craig ;

Hammerness, Paul ;

Doyle, Robert ;

Dougherty, Megan ;

Aleardi, Megan ;

Schweitzer, Karl .

CNS SPECTRUMS, 2006, 11 (05) :390-396

[8] Development and validation of the Self-Esteem And Relationship (SEAR) questionnaire in erectile dysfunction [J].

Cappelleri, JC ;

Althof, SE ;

Siegel, RL ;

Shpilsky, A ;

Bell, SS ;

Duttagupta, S .

INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH, 2004, 16 (01) :30-38

[9]

Conners C. K., 1999, CONNERSADULT ADHD RA

[10]

CRONBACH LJ, 1951, PSYCHOMETRIKA, V16, P297, DOI DOI 10.1007/BF02310555

← 1 2 3 4 →