Leprosy: A Review of Epidemiology, Clinical Diagnosis, and Management

被引：65

作者：

Chen, Kou-Huang ^{[1
]}

Lin, Cheng-Yao ^{[2
,3
,4
]}

Su, Shih-Bin ^{[5
]}

Chen, Kow-Tong ^{[6
,7
]}

机构：

[1] Sanming Univ, Sch Mech & Elect Engn, Sanming, Fujian, Peoples R China

[2] Chi Mei Med Ctr, Dept Internal Med, Div Hematol Oncol, Tainan, Taiwan

[3] Southern Taiwan Univ Sci & Technol, Dept Sr Welf & Serv, Tainan, Taiwan

[4] Natl Cheng Kung Univ, Dept Environm & Occupat Hlth, Tainan, Taiwan

[5] Chi Mei Med Ctr, Dept Occupat Med, Tainan, Taiwan

[6] Tainan Municipal Hosp, Dept Occupat Med, Show Chwan Med Care Corp, Tainan, Taiwan

[7] Natl Cheng Kung Univ, Coll Med, Dept Publ Hlth, Tainan, Taiwan

来源：

JOURNAL OF TROPICAL MEDICINE | 2022年 / 2022卷

关键词：

SLIT-SKIN SMEAR; MYCOBACTERIUM-LEPRAE DNA; CHILDHOOD LEPROSY; ENDEMIC AREA; LUCIOS PHENOMENON; BCG VACCINATION; BIOPSY SAMPLES; I ANTIBODY; CHILDREN; ELIMINATION;

D O I：

10.1155/2022/8652062

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Leprosy is a neglected infectious disease caused by acid-fast bacillus Mycobacterium leprae. It primarily affects the skin and then progresses to a secondary stage, causing peripheral neuropathy with potential long-term disability along with stigma. Leprosy patients account for a significant proportion of the global disease burden. Previous efforts to improve diagnostic and therapeutic techniques have focused on leprosy in adults, whereas childhood leprosy has been relatively neglected. This review aims to update the diagnostic and therapeutic recommendations for adult and childhood leprosy. This review summarizes the clinical, bacteriological, and immunological approaches used in the diagnosis of leprosy. As strategies for the diagnosis and management of leprosy continue to develop better and more advanced knowledge, control and prevention of leprosy are crucial.

引用

页数：13

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