Cu@KF/Clinoptilolite Nanoparticles Promoted Green Synthesis of Pyrimidine Derivatives: Study of Antioxidant Activity

被引:10
作者
Ahmadi, Naser [1 ]
Sayyed-Alangi, S. Zahra [1 ]
Varasteh-Moradi, Ali [2 ]
机构
[1] Islamic Azad Univ, Dept Chem, Azadshahr Branch, Azadshahr, Iran
[2] Islamic Azad Univ, Dept Chem, Gorgan Branch, Gorgan, Golestan, Iran
关键词
ability of oxidation; Cu@KF; CP; DPPH radical trapping; pyrimidine; EFFICIENT SYNTHESIS; HETEROGENEOUS CATALYST; COUPLING REACTIONS; ZEOLITE FRAMEWORK; NATROLITE ZEOLITE; ORGANIC-SYNTHESIS; MCF-7; BREAST; NANOCLUSTERS; NANOCATALYST; HYDROGENATION;
D O I
10.1080/10406638.2021.1912124
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The preparation of pyrrolo pyrimidinone derivatives were performed by using four component reactions of N-alkyl or aryl acetamides, dialkyloxalate, aldehydes, and guanidine in the presence of catalytic amounts of Cu@KF/CP NPs as a high performance catalyst in water at room temperature. In addition, for investigation of antioxidant ability radical trapping by DPPH and reducing power of ferric ion experiments was performed. As a result, synthesized compounds show excellent radical trapping by DPPH and good reducing ability of ferric ion. The current procedure has the benefits for instance excellent yield of reaction, green media and easy separation of product and catalyst.
引用
收藏
页码:4019 / 4033
页数:15
相关论文
共 73 条
[1]   Antioxidant activity of Kelussia odoratissima Mozaff. in model and food systems [J].
Ahmadi, Fatemeh ;
Kadivar, Mahdi ;
Shahedi, Mohammad .
FOOD CHEMISTRY, 2007, 105 (01) :57-64
[2]   Pd (II) Immobilized on Clinoptilolite as a Highly Active Heterogeneous Catalyst for Ullmann Coupling-type S-arylation of Thiols with Aryl Halides [J].
Alizadeh, Abdollah ;
Khalilzadeh, Mohammad A. ;
Alipour, Eskandar ;
Zareyee, Daryoush .
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2020, 23 (07) :658-666
[3]   An efficient one-pot multicomponent approach to 5-amino-7-aryl-8-nitrothiazolo[3,2-a]pyridines [J].
Altug, Cevher ;
Burnett, Alan K. ;
Caner, Esra ;
Durust, Yasar ;
Elliott, Mark C. ;
Glanville, Roger P. J. ;
Guy, Carol ;
Westwell, Andrew D. .
TETRAHEDRON, 2011, 67 (49) :9522-9528
[4]   Preparation and catalytic evaluation of a palladium catalyst deposited over modified clinoptilolite (Pd@MCP) for chemoselective N-formylation and N-acylation of amines [J].
Amirsoleimani, Mina ;
Khalilzadeh, Mohammad A. ;
Zareyee, Daryoush .
JOURNAL OF MOLECULAR STRUCTURE, 2021, 1225
[5]   Nano-sized clinoptilolite as a green catalyst for the rapid and chemoselective N-formylation of amines [J].
Amirsoleimani, Mina ;
Khalilzadeh, Mohammad A. ;
Zareyee, Daryoush .
REACTION KINETICS MECHANISMS AND CATALYSIS, 2020, 131 (02) :859-873
[6]   Natural Indian Natrolite zeolite-supported Cu nanoparticles: a new and reusable heterogeneous catalyst for N-arylation of sulfonamides with boronic acids in water under ligand-free conditions [J].
Azarifar, Davood ;
Soleimanei, Fatemeh .
RSC ADVANCES, 2014, 4 (24) :12119-12126
[7]   Lipid peroxidation and cataracts: N-Acetylcarnosine as a therapeutic tool to manage age-related cataracts in human and in canine eyes [J].
Babizhayev M.A. ;
Deyev A.I. ;
Yermakova V.N. ;
Brikman I.V. ;
Bours J. .
Drugs in R & D, 2004, 5 (3) :125-139
[8]   Pd-assisted multicomponent synthesis of heterocycles [J].
Balme, G ;
Bossharth, E ;
Monteiro, N .
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2003, 2003 (21) :4101-4111
[9]   An efficient and reusable nano catalyst for the synthesis of benzoxanthene and chromene derivatives [J].
Balou, Javad ;
Khalilzadeh, Mohammad A. ;
Zareyee, Daryoush .
SCIENTIFIC REPORTS, 2019, 9 (1)
[10]   KF/Nano-clinoptilolite Catalyzed Aldol-Type Reaction of Aldehydes with Ethyl Diazoacetate [J].
Balou, Javad ;
Khalilzadeh, Mohammad A. ;
Zareyee, Dariush .
CATALYSIS LETTERS, 2017, 147 (10) :2612-2618