Potent antiinflammatory 3-thiazole-4(5)-acetic acids of 1,2-benzisothiazole

被引：35
作者：
Sharma, PK
Sawhney, SN
机构：
[1] Department of Chemistry, Kurukshetra University
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1997年 / 7卷 / 18期
关键词：
D O I：
10.1016/S0960-894X(97)00449-6
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A number of 1,2-benzisothiazole derivatives, having 2-thiazolyl-4(5)-acetic acid moiety attached to position-3 of 1,2-benzisothiazole nucleus, were prepared and evaluated as antiinflammatory agents. Some of these were found to possess excellent level of antiinflammatory activity in carrageenin-induced rat paw edema assay. (C) 1997 Elsevier Science Ltd.
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页码：2427 / 2430
页数：4
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