Prevalence of Toxoplasma gondii and Toxocara canis among Patients with Uveitis

被引：8
作者：
Lim, Su Jin [1 ]
Lee, Sang Eun [2 ]
Kim, Sun Hyun [1 ]
Hong, Sung-Hee [2 ]
You, Yong Sung [1 ]
Kwon, Oh Woong [1 ]
Kim, Hyeun Seung [3 ]
机构：
[1] Nune Eye Hosp, Retina Ctr, Seoul, South Korea
[2] Korea Natl Inst Hlth, Ctr Dis Control & Prevent, Div Malaria & Parasit Dis, Seoul, South Korea
[3] Catholic Univ Korea, St Marys Hosp, Dept Ophthalmol & Visual Sci, Seoul 150713, South Korea
来源：
OCULAR IMMUNOLOGY AND INFLAMMATION | 2014年 / 22卷 / 05期
关键词：
Ocular toxocariasis; ocular toxoplasmosis; parasite; serologic test; uveitis; OCULAR TOXOCARIASIS; CLINICAL-FEATURES; POSTERIOR UVEITIS; CHAIN-REACTION; LARVA MIGRANS; DIAGNOSIS; DISEASE; JAPAN; DEXAMETHASONE; EPIDEMIOLOGY;
D O I：
10.3109/09273948.2013.841491
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Purpose: To investigate the prevalence of Toxoplasma gondii and Toxocara canis in patients with uveitis. Method: Patients with uveitis were examined. Serum antibodies to T. gondii and T. canis were tested by using enzyme-linked immunosorbent assay (ELISA). Polymerase chain reaction (PCR) was done using blood and aqueous humor (AH). Results: 98 patients were enrolled. Mean age was 43.5 +/- 13.2 years. Six patients were seropositive for T. gondii with the following pattern-anterior uveitis: 1; posterior uveitis with retinitis: 2; pan uveitis: 2. One patient had a positive result of PCR for T. gondii in AH, who showed pan uveitis. 23 patients were positive to serum IgG for T. canis with the following clinical manifestation-granuloma: 6; pigmented scar: 3; virtrits: 6-but none were PCR positive. Conclusion: T. gondii and T. canis are still one of the important causes of uveitis. Ocular toxocariasis is not an uncommon cause of uveitis even in adult.
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页码：360 / 366
页数：7
相关论文
共 34 条
[1]  
[Anonymous], GLOB TUB CONTR SURV
[2]   A Comparison Between the Fluocinolone Acetonide (Retisert) and Dexamethasone (Ozurdex) Intravitreal Implants in Uveitis [J].
Arcinue, Cheryl A. ;
Ceron, Olga M. ;
Foster, C. Stephen .
JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, 2013, 29 (05) :501-507
[3]   Modification of gDNA extraction from soil for PCR designed for the routine examination of soil samples contaminated with Toxocara spp. eggs [J].
Borecka, A. ;
Gawor, J. .
JOURNAL OF HELMINTHOLOGY, 2008, 82 (02) :119-122
[4]   IgG avidity assay firms up the diagnosis of acute toxoplasmosis on the first serum sample in immunocompetent pregnant women [J].
Candolfi, Ermanno ;
Pastor, Rebecca ;
Huber, Rachel ;
Filisetti, Denis ;
Villard, Odile .
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 2007, 58 (01) :83-88
[5]   Diagnosis of ocular toxocariasis by establishing intraocular antibody production [J].
De Visser, Lenneke ;
Rothova, Aniki ;
De Boer, Joke H. ;
Van Loon, Anton M. ;
Kerkhoff, Frank T. ;
Dijk, Marijke R. Canninga-Van ;
Weersink, Annemarie Y. L. ;
De Groot-Mijnes, Jolanda D. F. .
AMERICAN JOURNAL OF OPHTHALMOLOGY, 2008, 145 (02) :369-374
[6]   Toxocariasis: Clinical aspects, epidemiology, medical ecology, and molecular aspects [J].
Despommier, D .
CLINICAL MICROBIOLOGY REVIEWS, 2003, 16 (02) :265-+
[7]  
EM D., 1999, FOC POINTS CLIN MOD
[8]  
Gallian P CP, 2003, EVALUATION AUTOMATE
[9]   Ocular Toxoplasmosis: Clinical Characteristics in Pediatric Patients [J].
Garza-Leon, Manuel ;
Arellanes Garcia, Lourdes .
OCULAR IMMUNOLOGY AND INFLAMMATION, 2012, 20 (02) :130-138
[10]   THE SPECTRUM OF OCULAR TOXOCARIASIS [J].
GILLESPIE, SH ;
DINNING, WJ ;
VOLLER, A ;
CROWCROFT, NS .
EYE, 1993, 7 :415-418
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