Aichi virus infection in children with acute gastroenteritis in Finland

被引：53

作者：

Kaikkonen, S. ^{[1
]}

Rasanen, S. ^{[1
]}

Ramet, M. ^{[2
,3
]}

Vesikari, T. ^{[1
,2
]}

机构：

[1] Univ Tampere, Sch Med, Vaccine Res Ctr, FIN-33520 Tampere, Finland

[2] Tampere Univ Hosp, Dept Paediat, Tampere, Finland

[3] Univ Tampere, Inst Med Technol, FIN-33520 Tampere, Finland

来源：

EPIDEMIOLOGY AND INFECTION | 2010年 / 138卷 / 08期

关键词：

Gastroenteritis; virology; REVERSE TRANSCRIPTION-PCR; MOLECULAR CHARACTERIZATION; GENETIC DIVERSITY; PREVALENCE; NOROVIRUS; EFFICACY; SEQUENCE; VACCINE; MEMBER;

D O I：

10.1017/S0950268809991300

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Aichi virus has been proposed as a novel causative agent of acute gastroenteritis. In addition to several Asian countries, South America and Africa, Aichi virus has also recently been found in Europe. Our objective was to study the causative role of Aichi virus in children with acute gastroenteritis in Finland. We analysed 595 stool specimens from infants in an efficacy trial of rotavirus vaccine and 468 stool specimens from children in a hospital-based epidemiological and aetiological study of acute gastroenteritis. The screening was done by nested reverse transcription polymerase chain reaction amplifying a 519-bp segment and a 223-bp segment in the 3CD junction region of non-structural proteins. Aichi virus was detected in five stool samples (0.5%), of which four were co-infections with other gastroenteritis viruses. Two Aichi virus genotypes, A and B, were found. Aichi virus appears to be rare in children with acute gastroenteritis in Finland.

引用

页码：1166 / 1171

页数：6

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