Unusual Sertoli Cell Tumor Associated With Sex Cord Tumor With Annular Tubules in Peutz-Jeghers Syndrome: Report of a Case and Review of the Literature on Ovarian Tumors in Peutz-Jeghers Syndrome

被引：18
作者：
Ravishankar, Sanjita [1 ,2 ,3 ]
Mangray, Shamlal [1 ,2 ,3 ]
Kurkchubasche, Arlet [1 ,2 ,3 ]
Yakirevich, Evgeny [1 ,2 ,3 ]
Young, Robert H. [4 ]
机构：
[1] Rhode Isl Hosp, Providence, RI USA
[2] Hasbro Childrens Hosp, Providence, RI USA
[3] Brown Univ, Alpert Med Sch, Providence, RI 02912 USA
[4] Harvard Univ, Massachusetts Gen Hosp, Sch Med, Boston, MA USA
来源：
INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY | 2016年 / 24卷 / 03期
关键词：
sex cord stromal tumors; Sertoli cell tumor; Peutz-Jeghers syndrome; ovarian neoplasms; GENITAL-TRACT TUMORS; PRECOCIOUS PUBERTY; ADENOMA MALIGNUM; STK11; GENE; CANCER; MUTATIONS; CERVIX; WOMAN; GIRL;
D O I：
10.1177/1066896915620663
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
We report the case of an 11-year-old girl with Peutz-Jeghers syndrome and a unilateral ovarian tumor most consistent with Sertoli cell tumor associated with sex cord tumor with annular tubules. The ovary was replaced by a lobular, solid, yellow tumor. Microscopic examination showed 2 components that focally merged. The first was composed of uniform, cytologically bland cells arranged mostly in diffuse sheets and focally in tubules. The second showed typical sex cord tumor with annular tubules with extensive calcification. The predominant component of the tumor clearly fell in the sex cord category and most closely resembled Sertoli cell tumor. This case adds to the limited information on ovarian sex cord tumors, other than typical sex cord tumor with annular tubules, arising in association with Peutz-Jeghers syndrome, a topic reviewed herein.
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收藏
页码：269 / 273
页数：5
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