Supranuclear gaze palsy and opsoclonus after Diazinon poisoning

被引：11
作者：
Liang, TW
Balcer, LJ
Solomon, D
Messé, SR
Galetta, SL
机构：
[1] Univ Penn, Sch Med, Dept Neurol, Philadelphia, PA 19104 USA
[2] Univ Penn, Sch Med, Dept Ophthalmol, Philadelphia, PA 19104 USA
来源：
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 2003年 / 74卷 / 05期
关键词：
D O I：
10.1136/jnnp.74.5.677
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
A 52 year old man developed a supranuclear gaze palsy and opsoclonus after Diazinon poisoning. The diagnosis was confirmed by low plasma and red blood cell cholinesterase activity and urine mass spectroscopy. Saccadic control may be mediated in part by acetylcholine. Opsoclonus in the setting of organophosphate intoxication may occur as a result of cholinergic excess which overactivates the fastigial nuclei.
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页码：677 / 679
页数：3
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