A prospective study of alcoholism and the risk of Parkinson's disease

被引：47
作者：
Hernán, MA
Logroscino, G
Rodriguez, LAG
机构：
[1] Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA
[2] Ctr Espanol Invest Farmacoepidemiol, Madrid, Spain
来源：
JOURNAL OF NEUROLOGY | 2004年 / 251卷 / Suppl 7期
关键词：
alcoholism; Parkinson's disease; prospective studies;
D O I：
10.1007/s00415-004-1705-4
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The lower incidence of Parkinson's disease (PD) among smokers may be explained by a protective effect of cigarette smoke, or by a tendency to avoid addictive behaviors among future PD cases. We conducted an indirect test of the latter hypothesis by comparing the incidence of PD between alcoholics and nonalcoholics in the General Practice Research Database of the United Kingdom. Our case-control study included 1,019 cases and 10,123 matched controls. Overall, we did not find a lower incidence of PD among alcoholics compared with nonalcoholics (odds ratio: 1.09; 95 % Cl: 0.67, 1.78).
引用
收藏
页码：14 / 17
页数：4
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