Use of viscoelastic monitoring and prothrombin complex concentrate in a paediatric patient with polytrauma and severe traumatic brain injury

被引:0
作者
Sribnick, Eric A. [1 ,2 ]
Wenger, Nicole [3 ]
Nicol, Kathleen [4 ,5 ]
Tobias, Joseph D. [6 ,7 ]
机构
[1] Nationwide Childrens Hosp, Dept Neurosurg, Columbus, OH 43205 USA
[2] Ohio State Univ, Coll Med, Dept Neurosurg, Columbus, OH 43210 USA
[3] Ohio State Univ, Coll Med, Columbus, OH 43210 USA
[4] Nationwide Childrens Hosp, Dept Pathol & Lab Med, Columbus, OH USA
[5] Ohio State Univ, Coll Med, Dept Pathol, Columbus, OH 43210 USA
[6] Nationwide Childrens Hosp, Dept Anesthesiol & Pain Med, Columbus, OH USA
[7] Ohio State Univ, Coll Med, Dept Anesthesiol & Pain Med, Columbus, OH 43210 USA
关键词
haematology (incl blood transfusion); neurological injury; orthopaedics; neurosurgery; paediatric intensive care; COAGULATION MANAGEMENT; CARDIAC-SURGERY; NEUROSURGICAL PATIENTS; INTRACEREBRAL HEMORRHAGE; PERIOPERATIVE ASSESSMENT; REFERENCE RANGES; COAGULOPATHY; THROMBOELASTOGRAPHY; THROMBELASTOGRAPHY; TRANSFUSION;
D O I
10.1136/bcr-2020-236608
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Viscoelastic monitoring (VEM) tools, such as rotational thrombelastometry, have been used extensively to measure coagulopathy in adults but have received less attention in paediatric care. The presented case involves a 5-year-old boy who was brought to the emergency department after a motor vehicle collision with a Glasgow Coma Scale score of 6T and extensive injuries, including a subdural hematoma. VEM was used to monitor the patient's coagulopathy and to inform treatment measures by allowing real-time visualisation of the patient's coagulation status. VEM was additionally used to direct blood product replacement in preparation for neurosurgical intervention, and 4-factor prothrombin complex concentrate (PCC) was used to help reverse the coagulopathy. The patient underwent successful hemicraniectomy after improvement of his coagulopathy. In paediatrics, VEM and PCC are increasingly being used for post-trauma coagulopathy, and this case highlights their potential promise and the need for further research.
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页数:5
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