Synthesis of 2,3-dihydro-4(1H)-quinazolinones

被引：7

作者：

Escalante, J ^{[1
]}

Flores, P ^{[1
]}

Priego, JM ^{[1
]}

机构：

[1] Morelos Autonomous State Univ, Chem Res Ctr, Cuernavaca 62210, Morelos, Mexico

来源：

HETEROCYCLES | 2004年 / 63卷 / 09期

关键词：

D O I：

10.3987/COM-04-10130

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An improved procedure for the synthesis of 2-substituted 2,3-dihydro-4(1H)-quinazolinones through diastereomer separation of the corresponding quinazolinones derivatives is presented. The determination of their absolute configurations was obtained by X-Ray diffraction.

引用

页码：2019 / 2032

页数：14

共 24 条

[1] AN ANTIMALARIAL ALKALOID FROM HYDRANGEA .18. DERIVATIVES OF 4-PYRIMIDONE [J].

BAKER, BR ;

SCHAUB, RE ;

JOSEPH, JP ;

MCEVOY, FJ ;

WILLIAMS, JH .

JOURNAL OF ORGANIC CHEMISTRY, 1953, 18 (02) :133-137

[2] AROMATIC-AROMATIC INTERACTION - A MECHANISM OF PROTEIN-STRUCTURE STABILIZATION [J].

BURLEY, SK ;

PETSKO, GA .

SCIENCE, 1985, 229 (4708) :23-28

[3] SYNTHESIS OF CHIRAL 3-SUBSTITUTED 2,4(1H,3H)-QUINAZOLINEDIONES [J].

CANONNE, P ;

AKSSIRA, M ;

DAHDOUH, A ;

KASMI, H ;

BOUMZEBRA, M .

HETEROCYCLES, 1993, 36 (06) :1305-1314

[4] Studies on quinazolines.: 11.: Intramolecular imidate-amide rearrangement of 2-substituted 4-(ω-chloroalkoxy)quinazoline derivatives.: 1,3-O → N shift of chloroalkyl groups via cyclic 1,3-azaoxonium intermediates [J].

Chen, GS ;

Kalchar, S ;

Kuo, CW ;

Chang, CS ;

Usifoh, CO ;

Chern, JW .

JOURNAL OF ORGANIC CHEMISTRY, 2003, 68 (06) :2502-2505

[5] Isatoic anhydride I Reactions with primary and secondary amines and with some amides [J].

Clark, RH ;

Wagner, EC .

JOURNAL OF ORGANIC CHEMISTRY, 1944, 9 (01) :55-67

[6]

Connolly DJ, 2001, SYNLETT, P1707

[7]

COUTURE A, 1991, SYNTHESIS-STUTTGART, P1009

[8]

ESCALANTE J, 2001, REV SOC QUIM MEXICO, V0045

[9] FORMATION OF 1,2-DIHYDROQUINAZOLIN-4(3H)-ONES - REINVESTIGATION OF A RECENTLY REPORTED 1,3,4-BENZOTRIAZEPINE SYNTHESIS [J].

FULOP, F ;

SIMEONOV, M ;

PIHLAJA, K .

TETRAHEDRON, 1992, 48 (03) :531-538

[10] Stacking of six-membered aromatic rings in crystals [J].

Glówka, ML ;

Martynowski, D ;

Kozlowska, K .

JOURNAL OF MOLECULAR STRUCTURE, 1999, 474 :81-89

← 1 2 3 →