High-strength apatitic cement by modification with superplasticizers

被引:29
作者
Fernández, E
Sarda, S
Hamcerencu, M
Vlad, MD
Gel, M
Valls, S
Torres, R
López, J
机构
[1] Tech Univ Catalonia, IRGASC, Div Bioengn & Biomat, UPC, E-08028 Barcelona, Spain
[2] Univ Toulouse 3, LCBM, IUT A, F-81100 Castres, France
[3] UPC, Dept Bldg Engn, E-08034 Barcelona, Spain
关键词
calcium phosphate cement; bone tissue engineering; mechanical properties; osteoporosis; superplasticizer;
D O I
10.1016/j.biomaterials.2004.07.043
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
This study reports on a novel method to improve the strength of apatitic bone cements. The liquid phase of Biocement-H-(C) was modified with commercial superplasticizers. The results showed that small additions, i.e. 0.5 vol%, in the aqueous liquid phase improved the maximum compressive strength of Biocement-H-(C) (35 MPa) by 71 %, i.e. 60 MPa. Moreover, the addition of high amounts of superplasticizers, i.e. 50 vol.%, allowed for a significant reduction of the liquid-to-powder ratio from 0.32 to 0.256 mL/g, without affecting the maximum strength and/or the workability of the cement. These results open up new ways to develop injectable and high-strength apatitic bone cements for load-bearing applications. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码:2289 / 2296
页数:8
相关论文
共 27 条
[1]   Fabrication of low temperature macroporous hydroxyapatite scaffolds by foaming and hydrolysis of an α-TCP paste [J].
Almirall, A ;
Larrecq, G ;
Delgado, JA ;
Martínez, S ;
Planell, JA ;
Ginebra, MP .
BIOMATERIALS, 2004, 25 (17) :3671-3680
[2]  
*ASTM, 1993, ANN BOOK ASTM STAND, P189
[3]   Preparation of macroporous calcium phosphate cement tissue engineering scaffold [J].
Barralet, JE ;
Grover, L ;
Gaunt, T ;
Wright, AJ ;
Gibson, IR .
BIOMATERIALS, 2002, 23 (15) :3063-3072
[4]   High-strength apatitic cement by modification with α-hydroxy acid salts [J].
Barralet, JE ;
Hofmann, M ;
Grover, LM ;
Gbureck, U .
ADVANCED MATERIALS, 2003, 15 (24) :2091-+
[5]   Physical and chemical aspects of calcium phosphates used in spinal surgery [J].
Bohner, M .
EUROPEAN SPINE JOURNAL, 2001, 10 (Suppl 2) :S114-S121
[6]   An ultrasonic pulse-echo technique for monitoring the setting of CaSO4-based bone cement [J].
Carlson, J ;
Nilsson, M ;
Fernández, E ;
Planell, JA .
BIOMATERIALS, 2003, 24 (01) :71-77
[7]   A new method to produce macropores in calcium phosphate cements [J].
del Real, RP ;
Wolke, JGC ;
Vallet-Regí, M ;
Jansen, JA .
BIOMATERIALS, 2002, 23 (17) :3673-3680
[8]  
Fernandez E, 1996, J BIOMED MATER RES, V32, P367, DOI 10.1002/(SICI)1097-4636(199611)32:3<367::AID-JBM9>3.0.CO
[9]  
2-Q
[10]   An experimental approach to the study of the rheology behaviour of synthetic bone calcium phosphate cements [J].
Friberg, J ;
Fernández, E ;
Sarda, S ;
Nilsson, M ;
Ginebra, MP ;
Martínez, S ;
Planell, JA .
BIOCERAMICS, 2000, 192-1 :777-780