Influence of the Angelina Jolie Announcement and Insurance Reimbursement on Practice Patterns for Hereditary Breast Cancer

被引：26

作者：

Lee, Jihyoun ^{[1
]}

Kim, Sungwon ^{[2
]}

Kang, Eunyoung ^{[3
]}

Park, Suyeon ^{[4
]}

Kim, Zisun ^{[5
]}

Lee, Min Hyuk ^{[1
]}

机构：

[1] Soonchunhyang Univ, Dept Surg, Seoul Hosp, Seoul, South Korea

[2] Daerim St Marys Hosp, Dept Surg, 657 Siheung Daero, Seoul 07442, South Korea

[3] Seoul Natl Univ, Dept Surg, Bundang Hosp, Coll Med, Seongnam, South Korea

[4] Soonchunhyang Univ, Dept Biostat, Coll Med Sci, Seoul, South Korea

[5] Soonchunhyang Univ, Dept Surg, Bucheon Hosp, Bucheon, South Korea

来源：

JOURNAL OF BREAST CANCER | 2017年 / 20卷 / 02期

关键词：

Breast neoplasms; Genetic testing; Insurance coverage; Practice patterns; Prophylactic mastectomy; RISK-REDUCING MASTECTOMY; IMPACT;

D O I：

10.4048/jbc.2017.20.2.203

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Lack of awareness, the stigma of carrying a genetic mutation, and economic factors are barriers to acceptance of BRCA genetic testing or appropriate risk management. We aimed to investigate the influence of Angelina Jolie's announcement of her medical experience and also health insurance reimbursement for BRCA gene testing on practice patterns for hereditary breast and ovarian cancer (HBOC). A survey regarding changes in practice patterns for HBOC before and after the announcement was conducted online. The rate of BRCA gene testing was obtained from the National Health Insurance Review and Assessment Service database. From May to August 2016, 70 physicians responded to the survey. Genetic testing recommendations and prophylactic management were increased after the announcement. Risk-reducing salpingo-oophorectomy and contra lateral prophylactic mastectomy was significantly increased in BRCA carriers with breast cancer. The BRCA testing rate increased annually. Health insurance and a celebrity announcement were associated with increased genetic testing.

引用

页码：203 / 207

页数：5

共 14 条

[1] BRCA2 germline mutations in male breast cancer cases and breast cancer families [J].

Couch, FJ ;

Farid, LM ;

DeShano, ML ;

Tavtigian, SV ;

Calzone, K ;

Campeau, L ;

Peng, Y ;

Bogden, B ;

Chen, Q ;

Neuhausen, S ;

ShattuckEidens, D ;

Godwin, AK ;

Daly, M ;

Radford, DM ;

Sedlacek, S ;

Rommens, J ;

Simard, J ;

Garber, J ;

Merajver, S ;

Weber, BL .

NATURE GENETICS, 1996, 13 (01) :123-125

[2] Longer term effects of the Angelina Jolie effect: increased risk-reducing mastectomy rates in BRCA carriers and other high-risk women [J].

Evans, D. Gareth ;

Wisely, Julie ;

Clancy, Tara ;

Lalloo, Fiona ;

Wilson, Mary ;

Johnson, Richard ;

Duncan, Jonathon ;

Barr, Lester ;

Gandhi, Ashu ;

Howell, Anthony .

BREAST CANCER RESEARCH, 2015, 17

[3] The Angelina Jolie effect: how high celebrity profile can have a major impact on provision of cancer related services [J].

Evans, D. Gareth R. ;

Barwell, Julian ;

Eccles, Diana M. ;

Collins, Amanda ;

Izatt, Louise ;

Jacobs, Chris ;

Donaldson, Alan ;

Brady, Angela F. ;

Cuthbert, Andrew ;

Harrison, Rachel ;

Thomas, Sue ;

Howell, Anthony ;

Miedzybrodzka, Zosia ;

Murray, Alex .

BREAST CANCER RESEARCH, 2014, 16 (05)

[4] A Retrospective Exploration of the Impact of the 'Angelina Jolie Effect' on the Single State-Wide Familial Cancer Program in Perth, Western Australia [J].

Freedman, Rebecca ;

Mountain, Helen ;

Karina, Dian ;

Schofield, Lyn .

JOURNAL OF GENETIC COUNSELING, 2017, 26 (01) :52-62

[5] The Korean Hereditary Breast Cancer (KOHBRA) Study: Protocols and Interim Report [J].

Han, Sang Ah ;

Park, Sue K. ;

Ahn, Sei Hyun ;

Lee, Min Hyuk ;

Noh, Dong-Young ;

Kim, Lee Su ;

Noh, Woo-Chul ;

Jung, Yongsik ;

Kim, Ku Sang ;

Kim, Sung-Won .

CLINICAL ONCOLOGY, 2011, 23 (07) :434-441

[6] "Angelina effect" led to more appropriate breast cancer referrals, research shows [J].

Hawkes, Nigel .

BMJ-BRITISH MEDICAL JOURNAL, 2014, 349

[7] The Angelina Jolie effect [J].

James, Paul A. ;

Mitchell, Gillian ;

Bogwitz, Michael ;

Lindeman, Geoffrey J. .

MEDICAL JOURNAL OF AUSTRALIA, 2013, 199 (10) :646-646

[8] The Korean Hereditary Breast Cancer Study: Review and Future Perspectives [J].

Kang, Eunyoung ;

Kim, Sung-Won .

JOURNAL OF BREAST CANCER, 2013, 16 (03) :245-253

[9] The Change of Practice Patterns of the Hereditary Breast Cancer Management in Korea after the Korean Hereditary Breast Cancer Study [J].

Kang, Eunyoung ;

Ahn, Sei-Hyun ;

Noh, Woo-Chul ;

Noh, Dong-Young ;

Jung, Yongsik ;

Kim, Lee Su ;

Choi, Doo Ho ;

Suh, Young Jin ;

Kim, Ku Sang ;

Lee, Jeong Eon ;

Lee, Min Hyuk ;

Nam, Seok-Jin ;

Moon, Byung-In ;

Son, Byung Ho ;

Yang, Jung-Hyun ;

Yom, Cha Kyong ;

Kim, Sung Yong ;

Park, Sue K. ;

Kim, Sung-Won .

JOURNAL OF BREAST CANCER, 2010, 13 (04) :418-430

[10] Celebrity Influence and Identification: A Test of the Angelina Effect [J].

Kosenko, Kami A. ;

Binder, Andrew R. ;

Hurley, Ryan .

JOURNAL OF HEALTH COMMUNICATION, 2016, 21 (03) :318-326

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