Molecular genetics of affective disorders

被引：7

作者：

Oswald, P ^{[1
]}

Souery, D ^{[1
]}

Mendlewicz, J ^{[1
]}

机构：

[1] Free Univ Brussels, Hop Erasme, Dept Psychiat, B-1070 Brussels, Belgium

来源：

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY | 2004年 / 28卷 / 05期

关键词：

affective disorders; anticipation; association; ethics; linkage; molecular genetics;

D O I：

10.1016/j.pnpbp.2004.05.028

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Evidence for familial aggregation in Affective Disorders (AD) has been provided in classical studies. Linkage and association genetic studies have been proposed to detect genetic factors implicated in AD. However, findings from molecular genetic studies remain inconclusive. Nevertheless, current research is focusing on the phenotypes, both sub- and endophenotypes. In addition, recent advances in technology, such as microarrays, provide new tools in psychiatric genetics. These different approaches offer a new optimism era in the search of genetic factors in AD. (C) 2004 Elsevier Inc. All rights reserved.

引用

页码：865 / 877

页数：13

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