Factors affecting transfusion requirement after hip fracture: Can we reduce the need for blood?

被引:51
作者
Desai, Sagar J. [1 ]
Wood, Kristi S. [1 ]
Marsh, Jackie [1 ]
Bryant, Dianne [1 ]
Abdo, Hussein [1 ]
Lawendy, Abdel-Rahman [1 ]
Sanders, David W. [1 ]
机构
[1] Univ Western Ontario, London, ON, Canada
关键词
FEMORAL-NECK; DYNAMIC HIP; BACTERIAL-INFECTION; ELDERLY-PATIENTS; SURGERY; RISK; ASSOCIATION; MORTALITY; SCREW; DELAY;
D O I
10.1503/cjs.030413
中图分类号
R61 [外科手术学];
学科分类号
摘要
Background: Hip fractures are common injuries that result in blood loss and frequently require the transfusion of blood products. We sought to identify risk factors leading to increased blood transfusion in patients presenting with hip fractures, especially those factors that are modifiable. Methods: We retrospectively reviewed the cases of all patients who had fixation of their hip fractures between October 2005 and February 2010. The need for transfusion was correlated with potential risk factors, including age, sex, preoperative hemoglobin, fracture type, fixation method and more. Results: A total of 835 patients had fixation of their hip fractures during the study period; 631 met the inclusion criteria and 249 of them (39.5%) were transfused. We found an association between need for blood transfusion and female sex (p = 0.018), lower preoperative hemoglobin (p < 0.001), fracture type (p < 0.001) and fixation method (p < 0.001). Compared with femoral neck fractures, there was a 2.37 times greater risk of blood transfusion in patients with intertrochanteric fractures (p < 0.001) and a 4.03 times greater risk in those with subtrochanteric fractures (p < 0.001). Dynamic hip screw (DHS) fixation decreased the risk of transfusion by about half compared with intramedullary nail or hemiarthroplasty. We found no association with age, delay to operation (p = 0.17) or duration of surgery (p = 0.30). Conclusion: The only modifiable risk factor identified was fixation method. When considering blood transfusion requirements in isolation, we suggest a potential benefit in using a DHS for intertrochanteric and femoral neck fractures amenable to DHS fixation.
引用
收藏
页码:342 / 348
页数:7
相关论文
共 31 条
[1]   Blood transfusion requirements in elderly hip fracture patients [J].
Adunsky, A ;
Lichtenstein, A ;
Mizrahi, E ;
Arad, M ;
Heim, M .
ARCHIVES OF GERONTOLOGY AND GERIATRICS, 2003, 36 (01) :75-81
[2]   Liberal or Restrictive Transfusion in High-Risk Patients after Hip Surgery [J].
Carson, Jeffrey L. ;
Terrin, Michael L. ;
Noveck, Helaine ;
Sanders, David W. ;
Chaitman, Bernard R. ;
Rhoads, George G. ;
Nemo, George ;
Dragert, Karen ;
Beaupre, Lauren ;
Hildebrand, Kevin ;
Macaulay, William ;
Lewis, Courtland ;
Cook, Donald Richard ;
Dobbin, Gwendolyn ;
Zakriya, Khwaja J. ;
Apple, Fred S. ;
Horney, Rebecca A. ;
Magaziner, Jay .
NEW ENGLAND JOURNAL OF MEDICINE, 2011, 365 (26) :2453-2462
[3]   Risk of bacterial infection associated with allogeneic blood transfusion among patients undergoing hip fracture repair [J].
Carson, JL ;
Altman, DG ;
Duff, A ;
Noveck, H ;
Weinstein, MP ;
Sonnenberg, FA ;
Hudson, JI ;
Provenzano, G .
TRANSFUSION, 1999, 39 (07) :694-700
[4]   Epidemiology of osteoporosis [J].
Dennison, Elaine ;
Mohamed, Maysam Abdin ;
Cooper, Cyrus .
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA, 2006, 32 (04) :617-+
[5]   Preoperative characteristics identify patients with hip fractures at risk of transfusion [J].
Dillon, MF ;
Collins, D ;
Rice, J ;
Murphy, PG ;
Nicholson, P ;
Mac Elwaine, J .
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH, 2005, (439) :201-206
[6]   Prospective randomized comparison between a dynamic hip screw and a mini-invasive static nail in fractures of the trochanteric area: Preliminary results [J].
Dujardin, FH ;
Benez, C ;
Polle, G ;
Alain, J ;
Biga, N ;
Thomine, JM .
JOURNAL OF ORTHOPAEDIC TRAUMA, 2001, 15 (06) :401-406
[7]   ASSOCIATION BETWEEN BLOOD-TRANSFUSION AND INFECTION IN INJURED PATIENTS [J].
EDNA, TH ;
BJERKESET, T .
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 1992, 33 (05) :659-661
[8]  
Edna TH, 1998, EUR J SURG, V164, P449
[9]   The Effect of Erythrocyte Blood Transfusions on Survival After Surgery for Hip Fracture [J].
Engoren, Milo ;
Mitchell, Eric ;
Perring, Paul ;
Sferra, Joseph .
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 2008, 65 (06) :1411-1415
[10]   Mini-invasive nail versus DHS to fix pertrochanteric fractures: A case-control study [J].
Foulongne, E. ;
Gilleron, M. ;
Roussignol, X. ;
Lenoble, E. ;
Dujardin, F. .
ORTHOPAEDICS & TRAUMATOLOGY-SURGERY & RESEARCH, 2009, 95 (08) :592-598