Lipophilic rutin derivatives for antioxidant protection of oil-based foods

被引：109

作者：

Viskupicova, Jana ^{[1
,2
]}

Danihelova, Martina ^{[2
]}

Ondrejovic, Miroslav ^{[3
]}

Liptaj, Tibor ^{[4
]}

Sturdik, Ernest ^{[2
,3
]}

机构：

[1] Slovak Acad Sci, Inst Expt Pharmacol & Toxicol, Bratislava 84104, Slovakia

[2] Slovak Univ Technol Bratislava, Inst Biochem Nutr & Hlth Protect, Fac Chem & Food Technol, Bratislava 81243, Slovakia

[3] Univ Ss Cyril & Methodius, Dept Biotechnol, Fac Nat Sci, Trnava 91701, Slovakia

[4] Slovak Univ Technol Bratislava, Inst Analyt Chem, Fac Chem & Food Technol, Bratislava 81243, Slovakia

来源：

FOOD CHEMISTRY | 2010年 / 123卷 / 01期

关键词：

Acylation; Lipophilic esters; Rutin; Antioxidant potency; CANDIDA-ANTARCTICA LIPASE; OXIDATIVE STRESS; REGIOSELECTIVE ACYLATION; BIOCATALYTIC PREPARATION; ENZYMATIC-SYNTHESIS; ORGANIC-SOLVENTS; MAMMALIAN-CELLS; PLANT PIGMENTS; DNA-DAMAGE; FLAVONOIDS;

D O I：

10.1016/j.foodchem.2010.03.125

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The lipase-catalysed synthesis of lipophilic flavonoid antioxidants via rutin acylation with fatty acids (C4-C18) in 2-methylbutan-2-ol was investigated. Conversion yields of rutin fatty acid esters varied from 27% to 62%, depending on fatty acid chain length. Radical-scavenging capacity of compounds synthesized was evaluated against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, inhibition of lipid peroxidation was examined in beta-carotene linoleate system and their potential to act as food antioxidants was studied in sunflower oil using Rancimat test. The results suggest that lipophilic rutin esters, prepared via enzymatic esterification of rutin and fatty acids, may be useful agents in protection of oil-based foods against oxidation. Induction times of esters in the Rancimat test increased with their hydrophobicity. Esters of rutin with stearate, palmitate, oleate, linoleate and linolenate were found to be the most efficient agents of all compounds tested. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：45 / 50

页数：6

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