Cryosurgical monitoring using bioimpedance measurements - A feasibility study for electrical impedance tomography

被引：32

作者：

Otten, DM ^{[1
]}

Rubinsky, B ^{[1
]}

机构：

[1] Univ Calif Berkeley, Dept Mech Engn, Biomed Engn Lab, Berkeley, CA 94720 USA

来源：

IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING | 2000年 / 47卷 / 10期

基金：

美国国家科学基金会;

关键词：

bio-impedance; cryopreservation; cryosurgery; EIT; electrical impedance tomography;

D O I：

10.1109/10.871411

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

The effectiveness of cryosurgery in treating tumors is highly dependent on knowledge of freezing extent, and therefore relies heavily on real-time imaging techniques for monitoring. Electrical impedance tomography (EIT), which utilizes tissue impedance variation to construct an image, is very well suited to cryosurgery since frozen tissue impedance is much higher than that of unfrozen tissue, In this study, we explore cryosurgical monitoring as a previously uninvestigated application for EIT. The feasibility of bio-impedance measurements to detect ice front propagation is demonstrated by freezing planar tissue samples one-dimensionally while measuring impedance along a linear array. The experimental results compare favorably to a simple finite element model designed to provide an electrical field visualization tool.

引用

页码：1376 / 1381

页数：6

共 18 条

[1] Imaging with electricity: Report of the European Concerted Action on Impedance Tomography [J].

Boone, K ;

Barber, D ;

Brown, B .

JOURNAL OF MEDICAL ENGINEERING & TECHNOLOGY, 1997, 21 (06) :201-232

[2]

BROWN BH, 1982, P HOSP PHYS ANN C SH, V4, P1

[3] TISSUE IMPEDANCE AND TEMPERATURE-MEASUREMENTS IN RELATION TO NECROSIS IN EXPERIMENTAL CRYOSURGERY [J].

GAGE, AA ;

AUGUSTYNOWICZ, S ;

MONTES, M ;

CARUANA, JA ;

WHALEN, DA .

CRYOBIOLOGY, 1985, 22 (03) :282-288

[4] SPECIFIC RESISTANCE OF BIOLOGICAL MATERIAL-A COMPENDUM OF DATA FOR BIOMEDICAL ENGINEER AND PHYSIOLOGIST [J].

GEDDES, LA ;

BAKER, LE .

MEDICAL & BIOLOGICAL ENGINEERING, 1967, 5 (03) :271-&

[5] MEASUREMENT OF INTRA-TISSUE BIOELECTRICAL LOW-FREQUENCY IMPEDANCE - NEW METHOD TO PREDICT PER-OPERATIVELY DESTRUCTIVE EFFECT OF CRYOSURGERY [J].

LEPIVERT, PJ ;

BINDER, P ;

OUGIER, T .

CRYOBIOLOGY, 1977, 14 (02) :245-250

[6] CRYOBIOLOGY - FREEZING OF BIOLOGICAL SYSTEMS [J].

MAZUR, P .

SCIENCE, 1970, 168 (3934) :939-+

[7]

MORUCCI JP, 1991, P 13 ANN INT C IEEE, V13, P53

[8] ULTRASONIC CHARACTERISTICS OF FROZEN LIVER [J].

ONIK, G ;

COOPER, C ;

GOLDBERG, HI ;

MOSS, AA ;

RUBINSKY, B ;

CHRISTIANSON, M .

CRYOBIOLOGY, 1984, 21 (03) :321-328

[9]

ONIK G, 1994, PERCUTANEOUS PROSTAT

[10]

PEGG DE, 1988, NATO ASI SERIES A

← 1 2 →