Complete heart block in association with graft-versus-host disease

被引：18

作者：

Gilman, AL

Kooy, NW

Atkins, DL

Ballas, Z

Rumelhart, S

Holida, M

Lee, N

Goldman, F

机构：

[1] Univ Iowa, Coll Med, Dept Pediat, Div Hematol Oncol, Iowa City, IA 52242 USA

[2] Univ Iowa, Coll Med, Dept Pediat, Div Intens Care, Iowa City, IA 52242 USA

[3] Univ Iowa, Coll Med, Dept Pediat, Div Cardiol, Iowa City, IA 52242 USA

[4] Univ Iowa, Coll Med, Dept Med, Iowa City, IA 52242 USA

来源：

BONE MARROW TRANSPLANTATION | 1998年 / 21卷 / 01期

关键词：

cardiac; heart block; arrhythmia; graft-versus-host disease; bone marrow transplantation;

D O I：

10.1038/sj.bmt.1701038

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

An infant who received haploidentical BM for severe combined immunodeficiency (SCID) developed acute, reversible complete heart block in association with an exacerbation of GVHD, Respiratory distress and myocardial dysfunction were also seen with this and previous GVHD exacerbations, The patient had not received chemotherapy or radiation prior to BMT, The complete heart block resolved after 1 week of intensive immunosuppression. The association of complete heart block with GVHD is important because the heart block is potentially reversible with prompt, aggressive control of the GVHD.

引用

页码：85 / 88

页数：4

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