Brush-Like Polycarbonates Containing Dopamine, Cations, and PEG Providing a Broad-Spectrum, Antibacterial, and Antifouling Surface via One-Step Coating

被引：239

作者：

Yang, Chuan ^{[1
]}

Ding, Xin ^{[1
]}

Ono, Robert J. ^{[2
]}

Lee, Haeshin ^{[3
]}

Hsu, Li Yang ^{[4
]}

Tong, Yen Wah ^{[5
]}

Hedrick, James ^{[2
]}

Yang, Yi Yan ^{[1
]}

机构：

[1] Inst Bioengn & Nanotechnol, Singapore 138669, Singapore

[2] IBM Almaden Res Ctr, 650 Harry Rd, San Jose, CA 95120 USA

[3] Korea Adv Inst Sci & Technol, Dept Chem, Ctr Nat Inspired Technol KINC, Taejon 305701, South Korea

[4] Natl Univ Singapore Hosp, Singapore 119228, Singapore

[5] Natl Univ Singapore, Dept Chem & Biomol Engn, Singapore 117576, Singapore

来源：

ADVANCED MATERIALS | 2014年 / 26卷 / 43期

关键词：

POLY(ETHYLENE GLYCOL); SILVER NANOPARTICLES; MICROBIAL ADHESION; CATHETER COATINGS; CYCLIC CARBONATE; HYDROGELS;

D O I：

10.1002/adma.201402059

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An antibacterial and antifouling surface is obtained by simple one-step immersion of a catheter surface with brush-like polycarbonates containing pendent adhesive dopamine, antifouling polyethylene glycol (PEG), and antibacterial cations. This coating demonstrates excellent antibacterial and antifouling activities against both Gram-positive (S. aureus) and Gram-negative (E. coli) bacteria, proteins, and platelets, good stability under simulated blood-flow conditions, and no toxicity.

引用

页码：7346 / 7351

页数：6

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