Novel One-Pot Three Component Reaction for the Synthesis of [2-(Alkylsulfanyl)imidazo[1,2-a]pyridin-3-yl](aryl)methanone

被引：51
|
作者：
Kianmehr, Ebrahim [1 ]
Ghanbari, Mohammad [1 ]
Niri, Mehri Nadiri [1 ]
Faramarzi, Reza [1 ]
机构：
[1] Univ Tehran, Sch Chem, Coll Sci, Tehran, Iran
来源：
JOURNAL OF COMBINATORIAL CHEMISTRY | 2010年 / 12卷 / 01期
关键词：
MULTICOMPONENT REACTION; ANTIVIRAL ACTIVITY; SELECTIVE LIGANDS; BINDING-AFFINITY; C-NUCLEOSIDES; IN-VIVO; DERIVATIVES; INHIBITORS; CHEMISTRY; PYRIDINE;
D O I：
10.1021/cc900103r
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
A one-pot, three-component reaction between pyridine, phenacyl bromide, and thiocyanate is described. The reaction afforded the cot-responding special type of fully substituted imidazo[1,2-a]pyridine derivatives in good yields without using any catalyst or activation.
引用
收藏
页码：41 / 44
页数：4
相关论文
共 50 条
  • [21] Propargyl alcohol as an acrolein equivalent: synthesis of β-(3-indolyl)acroleins and β-(imidazo[1,2-a]pyridin-3-yl)acroleins
    Bhawani, Vikki N.
    Sonam, Prakash N.
    Shinde, Vikki N.
    Swami, Prakash N.
    Rangan, Krishnan
    Kumar, Anil
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2024, 22 (44) : 8720 - 8723
  • [22] Novel heterocyclic β-nitroenamines-based on a one-pot three-component reaction: a facile synthesis of fully substituted 1H-pyrrolo[1,2-a]-fused-1,3-diazaheterocycles
    Alizadeh, Abdolali
    Rezvanian, Atieh
    Deng, Yuan
    TETRAHEDRON, 2010, 66 (52) : 9933 - 9937
  • [23] Simple synthesis of benzo[g]imidazo[1,2-a]quinolinedione derivatives via a one-pot, four-component reaction
    Bayat, Mohammad
    Hosseini, Fahimeh
    Notash, Behrouz
    TETRAHEDRON LETTERS, 2016, 57 (49) : 5439 - 5441
  • [24] One-Pot Three-Component Reaction for Synthesis of Highly Substituted Pyrazolo[1,2-a][1,2,4]triazole Derivatives
    Sajadikhah, Seyed S.
    Maghsoodlou, Malek T.
    Hazeri, Nourallah
    Habibi-Khorassani, Sayyed M.
    LETTERS IN ORGANIC CHEMISTRY, 2011, 8 (10) : 743 - 748
  • [25] Synthesis and characterization of antibacterial 2-(pyridin-3-yl)-1H-benzo[d]imidazoles and 2-(pyridin-3-yl)-3H-imidazo[4,5-b]pyridine derivatives
    Mallemula, Venkata Ramakrishna
    Sanghai, Niraj Nemichand
    Himabindu, V.
    Chakravarthy, Akula Kalyan
    RESEARCH ON CHEMICAL INTERMEDIATES, 2015, 41 (04) : 2125 - 2138
  • [26] One-pot approach to the synthesis of novel 12H-chromeno[2′,3′:4,5]imidazo[1,2-a]pyridines in aqueous media
    Proenca, M. Fernanda
    Costa, Marta
    TETRAHEDRON, 2010, 66 (25) : 4542 - 4550
  • [27] One-Pot Synthesis of 2-(Alkylsulfanyl)quinolines from Aryl Isothiocyanates and Allenes or Alkynes
    Nedolya, Nina A.
    Tarasova, Ol'ga A.
    Artem'ev, Alexander V.
    Albanov, Alexander I.
    Bagryanskaya, Irina Yu.
    Trofimov, Boris A.
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2024, 27 (13)
  • [28] One-pot, three component tandem reaction of 2-aminopyridines, acetophenones and aldehydes: synthesis of 3-aroylimidazo[1,2-a] pyridines
    Kaswan, Pinku
    Pericherla, Kasiviswanadharaju
    Saini, Hitesh Kumar
    Kumar, Anil
    RSC ADVANCES, 2015, 5 (05): : 3670 - 3677
  • [29] Investigations on substituted (2-aminothiazol-5-yl)(imidazo[1,2-a]pyridin-3-yl)methanones for the treatment of Alzheimer's disease
    Sagar, Sneha R.
    Singh, Devendra Pratap
    Das, Rajesh D.
    Panchal, Nirupa B.
    Sudarsanam, Vasudevan
    Nivsarkar, Manish
    Vasu, Kamala K.
    BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 36
  • [30] One-pot three-component synthesis of 2-(3,5-diaryl-4,5-dihydropyrazol-1-yl)-1,3,4-thiadiazoles
    Li, Zheng
    Shi, Jinghong
    Yang, Jingya
    Liu, Chenhui
    Niu, Pengxian
    HETEROCYCLIC COMMUNICATIONS, 2012, 18 (02) : 99 - 102
12345