Novel One-Pot Three Component Reaction for the Synthesis of [2-(Alkylsulfanyl)imidazo[1,2-a]pyridin-3-yl](aryl)methanone

被引:51
|
作者
Kianmehr, Ebrahim [1 ]
Ghanbari, Mohammad [1 ]
Niri, Mehri Nadiri [1 ]
Faramarzi, Reza [1 ]
机构
[1] Univ Tehran, Sch Chem, Coll Sci, Tehran, Iran
来源
JOURNAL OF COMBINATORIAL CHEMISTRY | 2010年 / 12卷 / 01期
关键词
MULTICOMPONENT REACTION; ANTIVIRAL ACTIVITY; SELECTIVE LIGANDS; BINDING-AFFINITY; C-NUCLEOSIDES; IN-VIVO; DERIVATIVES; INHIBITORS; CHEMISTRY; PYRIDINE;
D O I
10.1021/cc900103r
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
A one-pot, three-component reaction between pyridine, phenacyl bromide, and thiocyanate is described. The reaction afforded the cot-responding special type of fully substituted imidazo[1,2-a]pyridine derivatives in good yields without using any catalyst or activation.
引用
收藏
页码:41 / 44
页数:4
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