Response-adapted consolidation with bortezomib after ASCT improves progression-free survival in newly diagnosed multiple myeloma

被引:21
作者
Einsele, H. [1 ]
Knop, S. [1 ]
Vogel, M. [2 ]
Mueller, J. [3 ]
Kropff, M. [4 ]
Metzner, B. [5 ]
Langer, C. [6 ]
Sayer, H. [7 ]
Jung, W. [8 ]
Duerk, H. A. [9 ]
Salwender, H. [10 ]
Wandt, H. [11 ]
Bassermann, F. [12 ]
Gramatzki, M. [13 ]
Roesler, W. [14 ]
Wolf, H-H [15 ]
Brugger, W. [16 ]
Engelhardt, M. [17 ]
Fischer, T. [18 ]
Liebisch, P. [6 ]
Straka, C. [19 ]
机构
[1] Julius Maximilians Univ Wurzburg, Med Klin & Poliklin 2, Wurzburg, Germany
[2] Janssen Cilag GmbH, Neuss, Germany
[3] Acromion GmbH, Frechen, Germany
[4] Univ Klinikum Munster, Munster, Germany
[5] Klinikum Oldenburg Klin Onkol & Hamatol, Oldenburg, Germany
[6] Univ Klinikum Ulm, Zentrum Innere Med, Ulm, Germany
[7] Univ Hosp Jena, Jena, Germany
[8] Onkol Univ Med Gottingen, Gottingen, Germany
[9] St Marien Hosp Hamm Knappenstr, Hamm, Germany
[10] Asklepios Klin Altona, Hamburg, Germany
[11] Med Klin 5 Hamatol & Onkol, Nurnberg, Germany
[12] Tech Univ Munich, Med Klin, Munich, Germany
[13] Univ Klinikum Schleswig Holstein, Kiel, Germany
[14] Univ Klinkum Erlangen, Erlangen, Germany
[15] Univ Hosp Halle, Halle, Saale, Germany
[16] Schwarzwald Baar Klinikum, Villingen Schwenningen, Germany
[17] Univ Freiburg, Freiburg, Germany
[18] Otto von Guericke Univ, Magdeburg, Germany
[19] Schon Klin Starnberger See, Berg, Germany
关键词
STEM-CELL TRANSPLANTATION; INDUCTION; THERAPY; PHASE-3;
D O I
10.1038/leu.2017.83
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:1463 / 1466
页数:5
相关论文
共 50 条
  • [31] Impact of maintenance therapy on subsequent treatment in patients with newly diagnosed multiple myeioma: use of "progression-free survival 2" as a clinical trial end-point
    Dimopoulos, Meletios A.
    Petrucci, Maria T.
    Foa, Robin
    Catalano, John
    Kropff, Martin
    Terpos, Evangelos
    Zhang, Jingshan
    Grote, Lara
    Jacques, Christian
    Palumbo, Antonio
    HAEMATOLOGICA, 2015, 100 (08) : E328 - E330
  • [32] Six-month progression-free survival as an alternative primary efficacy endpoint to overall survival in newly diagnosed glioblastoma patients receiving temozolomide
    Polley, Mei-Yin C.
    Lamborn, Kathleen R.
    Chang, Susan M.
    Butowski, Nicholas
    Clarke, Jennifer L.
    Prados, Michael
    NEURO-ONCOLOGY, 2010, 12 (03) : 274 - 282
  • [33] Tolerance, Kinetics, and Depth of Response for Subcutaneous Versus Intravenous Administration of Bortezomib Combination in Chinese Patients With Newly Diagnosed Multiple Myeloma
    Xu, Yan
    Deng, Shuhui
    Mao, Xuehan
    An, Gang
    Li, Zengjun
    Wang, Yafei
    Fulciniti, Mariateresa
    Ho, Matthew
    Lin, Jianhong
    Sui, Weiwei
    Liu, Wei
    Zou, Dehui
    Yi, Shuhua
    Huang, Wenyang
    Liu, Hong
    Lv, Rui
    Li, Jian
    Wang, Tingyu
    Du, Chenxing
    Munshi, Nikhil C.
    Qiu, Lugui
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2018, 18 (06) : 422 - 430
  • [34] Ixazomib, lenalidomide and dexamethasone consolidation with randomized ixazomib or lenalidomide maintenance after autologous transplant in newly diagnosed multiple myeloma
    Slade, Michael
    Martin, Thomas G.
    Nathwani, Nitya
    Fiala, Mark A.
    Rettig, Michael P.
    Gao, Feng
    Deol, Abhinav
    Buadi, Francis K.
    Kaufman, Jonathan L.
    Hofmeister, Craig C.
    Gregory, Tara K.
    Berdeja, Jesus
    Chari, Ajai
    Rosko, Ashley
    Vij, Ravi
    LEUKEMIA, 2022, 36 (12) : 2917 - 2921
  • [35] Association of Minimal Residual Disease Negativity Rates With Progression Free Survival in Frontline Therapy Trials for Newly Diagnosed Multiple Myeloma: A Meta-analysis
    Ficek, Joseph
    Kalaitzaki, Eleftheria
    Yuan, Shuai Sammy
    Tosolini, Alessandra
    Du, Ling
    Kremer, Brandon E.
    Davy, Katherine
    Zhou, Helen
    Chen, Tai-Tsang
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2023, 23 (05) : E213 - E221
  • [36] A steroid-independent regimen of bortezomib, liposomal doxorubicin and thalidomide demonstrate high response rates in newly diagnosed multiple myeloma patients
    Sher, Taimur
    Ailawadhi, Sikander
    Miller, Kena C.
    Manfredi, Debbie
    Wood, Margaret
    Tan, Wei
    Wilding, Gregory
    Czuczman, Myron S.
    Hernandez-Ilizaliturri, Francisco J.
    Hong, Fredrick
    Sood, Raman
    Soniwala, Saif
    Lawrence, William
    Jamshed, Saad
    Masood, Aisha
    Iancu, Daniel
    Lee, Kelvin
    Chanan-Khan, Asher
    BRITISH JOURNAL OF HAEMATOLOGY, 2011, 154 (01) : 104 - 110
  • [37] Combining bortezomib to high dose melphalan as conditioning regimen results in the improvement of the response rate in newly diagnosed young multiple myeloma patients
    Dalla Palma, Benedetta
    Accardi, Fabrizio
    Prezioso, Lucia
    Notarfranchi, Laura
    Giuliani, Nicola
    LEUKEMIA & LYMPHOMA, 2020, 61 (05) : 1238 - 1241
  • [38] Serum levels of soluble programmed death ligand 1 predict treatment response and progression free survival in multiple myeloma
    Wang, Liang
    Wang, Hua
    Chen, Hao
    Wang, Wei-da
    Chen, Xiao-qin
    Geng, Qi-rong
    Xia, Zhong-jun
    Lu, Yue
    ONCOTARGET, 2015, 6 (38) : 41228 - 41236
  • [39] A patient survey indicates quality of life and progression-free survival as equally important outcome measures in multiple myeloma clinical trials
    Fleischer, Anna
    Zapf, Larissa
    Allgaier, Johannes
    Jordan, Karin
    Gelbrich, Goetz
    Pryss, Ruediger
    Schobel, Johannes
    Bittrich, Max
    Einsele, Hermann
    Kortuem, Martin
    Maatouk, Imad
    Weinhold, Niels
    Rasche, Leo
    JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2023, 149 (14) : 12897 - 12902
  • [40] Thalidomide consolidation improves progression-free survival in myeloma with normal but not up-regulated expression of fibroblast growth factor receptor 3: analysis from the Australasian Leukaemia and Lymphoma Group MM6 clinical trial
    Ho, P. Joy
    Brown, Ross D.
    Spencer, Andrew
    Jeffels, Melinda
    Daniher, Daniel
    Gibson, John
    Joshua, Douglas E.
    LEUKEMIA & LYMPHOMA, 2012, 53 (09) : 1728 - 1734