Phase II trial of therapeutic vaccine consisting of autologous dendritic cells loaded with autologous tumor cell antigens from self-renewing cancer cells in patients with newly diagnosed glioblastoma

被引：0
|
作者：
Bota, Daniela [1 ]
Piccioni, David [2 ]
LaRocca, Renato [3 ]
Duma, Christopher [4 ]
Aiken, Robert [5 ]
Kesari, Santosh [6 ]
Carrillo, Jose [6 ]
Taylor, Thomas [1 ]
Hsieh, Candace [7 ]
Nistor, Gabriel [7 ]
Dillman, Robert [7 ]
机构：
[1] Univ Calif Irvine, Orange, CA 92668 USA
[2] Univ Calif San Diego, San Diego, CA 92103 USA
[3] Norton Hosp, Louisville, KY USA
[4] Hoag Hosp, Newport Beach, CA USA
[5] Rutgers State Univ, New Brunswick, NJ USA
[6] John Wayne Canc Inst, Santa Monica, CA USA
[7] AiVita Biomed Inc, Irvine, CA USA
来源：
JOURNAL FOR IMMUNOTHERAPY OF CANCER | 2019年 / 7卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
O22
引用
收藏
页数：2
相关论文
共 50 条
  • [41] ALLOGENEIC TUMOR LYSATE / AUTOLOGOUS DENDRITIC CELL VACCINES IN NEWLY DIAGNOSED GLIOBLASTOMA: CLINICAL TRIAL MC1272
    Parney, Ian F.
    Gustafson, Michael P.
    Peterson, Timothy
    Steinmetz, Susan M.
    Bulur, Peggy
    Dietz, Allan B.
    NEURO-ONCOLOGY, 2016, 18 : 24 - 25
  • [42] PHASE I/IIA TRIAL OF AUTOLOGOUS FORMALIN-FIXED TUMOR VACCINE IN TREATMENT OF NEWLY DIAGNOSED GLIOBLASTOMA MULTIFORME
    Muragaki, Yoshihiro
    Maruyama, Takashi
    Iseki, Hiroshi
    Takakura, Kintomo
    Tanaka, Masahiko
    Shinohara, Chie
    Tsuboi, Koji
    Yamamoto, Tetsuya
    Matsumura, Akira
    Matsutani, Masao
    Karasawa, Katsuyuki
    Ohno, Tadao
    Hori, Tomokatsu
    NEURO-ONCOLOGY, 2009, 11 (06) : 883 - 883
  • [43] First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma (vol 16, 142, 2018)
    Liau, Linda M.
    Ashkan, Keyoumars
    Tran, David D.
    Campian, Jian L.
    Trusheim, John E.
    Cobbs, Charles S.
    Heth, Jason A.
    Salacz, Michael
    Taylor, Sarah
    D'Andre, Stacy D.
    Iwamoto, Fabio M.
    Dropcho, Edward J.
    Moshel, Yaron A.
    Walter, Kevin A.
    Pillainayagam, Clement P.
    Aiken, Robert
    Chaudhary, Rekha
    Goldlust, Samuel A.
    Bota, Daniela A.
    Duic, Paul
    Grewal, Jai
    Elinzano, Heinrich
    Toms, Steven A.
    Lillehei, Kevin O.
    Mikkelsen, Tom
    Walbert, Tobias
    Abram, Steven R.
    Brenner, Andrew J.
    Brem, Steven
    Ewend, Matthew G.
    Khagi, Simon
    Portnow, Jana
    Kim, Lyndon J.
    Loudon, William G.
    Thompson, Reid C.
    Avigan, David E.
    Fink, Karen L.
    Geoffroy, Francois J.
    Lindhorst, Scott
    Lutzky, Jose
    Sloan, Andrew E.
    Schackert, Gabriele
    Krex, Dietmar
    Meisel, Hans-Jorg
    Wu, Julian
    Davis, Raphael P.
    Duma, Christopher
    Etame, Arnold B.
    Mathieu, David
    Kesari, Santosh
    JOURNAL OF TRANSLATIONAL MEDICINE, 2018, 16
  • [44] Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma A Phase 3 Prospective Externally Controlled Cohort Trial
    Liau, Linda M.
    Ashkan, Keyoumars
    Brem, Steven
    Campian, Jian L.
    Trusheim, John E.
    Iwamoto, Fabio M.
    Tran, David D.
    Ansstas, George
    Cobbs, Charles S.
    Heth, Jason A.
    Salacz, Michael E.
    D'Andre, Stacy
    Aiken, Robert D.
    Moshel, Yaron A.
    Nam, Joo Y.
    Pillainayagam, Clement P.
    Wagner, Stephanie A.
    Walter, Kevin A.
    Chaudary, Rekha
    Goldlust, Samuel A.
    Lee, Ian Y.
    Bota, Daniela A.
    Elinzano, Heinrich
    Grewal, Jai
    Lillehei, Kevin
    Mikkelsen, Tom
    Walbert, Tobias
    Abram, Steven
    Brenner, Andrew J.
    Ewend, Matthew G.
    Khagi, Simon
    Lovick, Darren S.
    Portnow, Jana
    Kim, Lyndon
    Loudon, William G.
    Martinez, Nina L.
    Thompson, Reid C.
    Avigan, David E.
    Fink, Karen L.
    Geoffroy, Francois J.
    Giglio, Pierre
    Gligich, Oleg
    Krex, Dietmar
    Lindhorst, Scott M.
    Lutzky, Jose
    Meisel, Hans-Jorg
    Nadji-Ohl, Minou
    Sanchin, Lhagva
    Sloan, Andrew
    Taylor, Lynne P.
    JAMA ONCOLOGY, 2023, 9 (01) : 112 - 121
  • [45] A phase I/II clinical trial investigating the adverse and therapeutic effects of a postoperative autologous dendritic cell tumor vaccine in patients with malignant glioma
    Chang, Chen-Nen
    Huang, Yin-Cheng
    Yang, Den-Mei
    Kikuta, Kenichiro
    Wei, Kuo-Jen
    Kubota, Toshihiko
    Yang, Wen-Kuang
    JOURNAL OF CLINICAL NEUROSCIENCE, 2011, 18 (08) : 1048 - 1054
  • [46] Therapeutic vaccination against autologous cancer stem cells with mRNA-transfected dendritic cells in patients with glioblastoma
    Einar Osland Vik-Mo
    Marta Nyakas
    Birthe Viftrup Mikkelsen
    Morten Carstens Moe
    Paulina Due-Tønnesen
    Else Marit Inderberg Suso
    Stein Sæbøe-Larssen
    Cecilie Sandberg
    Jan E. Brinchmann
    Eirik Helseth
    Anne-Marie Rasmussen
    Knut Lote
    Steinar Aamdal
    Gustav Gaudernack
    Gunnar Kvalheim
    Iver A. Langmoen
    Cancer Immunology, Immunotherapy, 2013, 62 : 1499 - 1509
  • [47] Tumor specific cytotoxicity and telomerase down-regulation in prostate cancer by autologous dendritic cells loaded with whole tumor cell antigens
    Turkeri, Levent
    Onol, Fikret Fatih
    Ozyurek, Mustafa
    UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, 2010, 28 (03) : 290 - 295
  • [48] Therapeutic vaccination against autologous cancer stem cells with mRNA-transfected dendritic cells in patients with glioblastoma
    Vik-Mo, Einar Osland
    Nyakas, Marta
    Mikkelsen, Birthe Viftrup
    Moe, Morten Carstens
    Due-Tonnesen, Paulina
    Suso, Else Marit Inderberg
    Saeboe-Larssen, Stein
    Sandberg, Cecilie
    Brinchmann, Jan E.
    Helseth, Eirik
    Rasmussen, Anne-Marie
    Lote, Knut
    Aamdal, Steinar
    Gaudernack, Gustav
    Kvalheim, Gunnar
    Langmoen, Iver A.
    CANCER IMMUNOLOGY IMMUNOTHERAPY, 2013, 62 (09) : 1499 - 1509
  • [49] Phase I/IIa trial of fractionated radiotherapy, temozolomide, and autologous formalin-fixed tumor vaccine for newly diagnosed glioblastoma
    Ishikawa, Eiichi
    Muragaki, Yoshihiro
    Yamamoto, Tetsuya
    Maruyama, Takashi
    Tsuboi, Koji
    Ikuta, Soko
    Hashimoto, Koichi
    Uemae, Youji
    Ishihara, Takeshi
    Matsuda, Masahide
    Matsutani, Masao
    Karasawa, Katsuyuki
    Nakazato, Yoichi
    Abe, Tatsuya
    Ohno, Tadao
    Matsumura, Akira
    JOURNAL OF NEUROSURGERY, 2014, 121 (03) : 543 - 553
  • [50] Early trial results of an autologous tumor lysate, particle-loaded, dendritic cell (TLPLDC) vaccine in ovarian cancer patients
    Peace, Kaitlin M.
    Vreeland, Timothy J.
    Clifton, Guy T.
    Hale, Diane F.
    Jackson, Doreen O.
    Berry, John S.
    Trappey, Alfred F.
    Herbert, Garth S.
    Hardin, Mark O.
    Nichol, Pauline T.
    Yin, Sook L.
    Yu, Xianzhong
    Wagner, Thomas E.
    Peoples, George E.
    CANCER RESEARCH, 2017, 77
12345