Near-infrared upconversion nanoparticles for bio-applications

被引：60

作者：

Dou, Qing Qing ^{[1
]}

Guo, Hong Chen ^{[1
]}

Ye, Enyi ^{[1
]}

机构：

[1] Inst Mat Res & Engn, Singapore 117602, Singapore

来源：

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS | 2014年 / 45卷

关键词：

NIR upconversion; Multi-modality; Photodynamic therapy; Photo activation; EMISSION CROSS-SECTION; QUANTUM DOTS; GDVO4; NANOCRYSTALS; WHITE-LIGHT; LUMINESCENCE; FLUORESCENCE; ER3+; SPECTROSCOPY; CRYSTALS; GREEN;

D O I：

10.1016/j.msec.2014.03.056

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

0805 ; 080501 ; 080502 ;

摘要：

Upconversion nanoparticles (UCNs) attract intensive attentions in biomedical applications. They have shown great potential in bioimaging, biomolecule detection, drug delivery, photodynamic therapy and cellular molecules interactions. Due to the anti-Stokes optical property! and NIR excitation, UCNs overcome the drawbacks encountered in conventional luminescent biomarkers. High signal to noise ratio, low cytotoxicity and stable high throughput results are obtained using UCNs as luminescent labels or light triggers in biomedical applications. In this review article, the reason for choosing UCNs as biomedical agents, the progress of the UCNs development and case studies of their biomedical applications will be discussed. (C) 2014 Elsevier B.V. All rights reserved.

引用

页码：635 / 643

页数：9

共 112 条

[1] Semiconductor clusters, nanocrystals, and quantum dots [J].