The mechanisms of action of rituximab in the elimination of tumor cells

被引:204
作者
Johnson, P [1 ]
Glennie, M [1 ]
机构
[1] Univ Southampton, Sch Med, Canc Sci Div, Southampton, Hants, England
关键词
D O I
10.1053/sonc.2003.50025
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:3 / 8
页数:6
相关论文
共 35 条
[1]  
Alas S, 2000, ANTICANCER RES, V20, P2961
[2]  
Alas S, 2001, CANCER RES, V61, P5137
[3]  
Alas S, 2001, CLIN CANCER RES, V7, P709
[4]   Targeted anti-cancer therapy using rituximab, a chimaeric anti-CD20 antibody (IDEC-C2B8) in the treatment of non-Hodgkin's B-cell lymphoma [J].
Anderson, DR ;
GrilloLopez, A ;
Varns, C ;
Chambers, KS ;
Hanna, N .
BIOCHEMICAL SOCIETY TRANSACTIONS, 1997, 25 (02) :705-708
[5]   TRANSFECTION OF THE CD20 CELL-SURFACE MOLECULE INTO ECTOPIC CELL-TYPES GENERATES A CA2+ CONDUCTANCE FOUND CONSTITUTIVELY IN B-LYMPHOCYTES [J].
BUBIEN, JK ;
ZHOU, LJ ;
BELL, PD ;
FRIZZELL, RA ;
TEDDER, TF .
JOURNAL OF CELL BIOLOGY, 1993, 121 (05) :1121-1132
[6]   The mechanism of tumor cell clearance by rituximab in vivo in patients with B-cell chronic lymphocytic leukemia: evidence of caspase activation and apoptosis induction [J].
Byrd, JC ;
Kitada, S ;
Flinn, IW ;
Aron, JL ;
Pearson, M ;
Lucas, N ;
Reed, JC .
BLOOD, 2002, 99 (03) :1038-1043
[7]   Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcγRIIIa gene [J].
Cartron, G ;
Dacheux, L ;
Salles, G ;
Solal-Celigny, P ;
Bardos, P ;
Colombat, P ;
Watier, H .
BLOOD, 2002, 99 (03) :754-758
[8]   Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets [J].
Clynes, RA ;
Towers, TL ;
Presta, LG ;
Ravetch, JV .
NATURE MEDICINE, 2000, 6 (04) :443-446
[9]   Rituximab (anti-CD20 monoclonal antibody) as single first-line therapy for patients with follicular lymphoma with a low tumor burden:: clinical and molecular evaluation [J].
Colombat, P ;
Salles, G ;
Brousse, N ;
Eftekhari, P ;
Soubeyran, P ;
Delwail, V ;
Deconinck, E ;
Haïoun, C ;
Foussard, C ;
Sebban, C ;
Stamatoullas, A ;
Milpied, N ;
Boué, F ;
Taillan, B ;
Lederlin, P ;
Najman, A ;
Thièblemont, C ;
Montestruc, F ;
Mathieu-Boué, A ;
Benzohra, A ;
Solal-Céligny, P .
BLOOD, 2001, 97 (01) :101-106
[10]   Rituximab in combination with CHOP or fludarabine in low-grade lymphoma [J].
Czuczman, MS ;
Fallon, A ;
Mohr, A ;
Stewart, C ;
Bernstein, ZP ;
McCarthy, P ;
Skipper, M ;
Brown, K ;
Miller, K ;
Wentling, D ;
Klippenstein, D ;
Loud, P ;
Rock, MK ;
Benyunes, M ;
Grillo-López, AJ ;
Bernstein, SH .
SEMINARS IN ONCOLOGY, 2002, 29 (01) :36-40