Multiplex imaging of live breast cancer tumour models through tissue using handheld surface enhanced spatially offset resonance Raman spectroscopy (SESORRS)

被引:32
作者
Nicolson, Fay [1 ]
Jamieson, Lauren E. [1 ]
Mabbott, Samuel [1 ]
Plakas, Konstantinos [2 ]
Shand, Neil C. [3 ]
Detty, Michael R. [2 ]
Graham, Duncan [1 ]
Faulds, Karen [1 ]
机构
[1] Univ Strathclyde, Dept Pure & Appl Chem, Technol & Innovat Ctr, 99 George St, Glasgow G1 1RD, Lanark, Scotland
[2] SUNY Buffalo, Dept Chem, Buffalo, NY 14260 USA
[3] DSTL, Salisbury SP4 0JQ, Wilts, England
基金
英国工程与自然科学研究理事会;
关键词
IN-VIVO; NANOSENSORS;
D O I
10.1039/c8cc04267e
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Through utilizing the depth penetration capabilities of SESORS, multiplexed imaging and classification of three singleplex nanotags and a triplex of nanotags within breast cancer tumour models is reported for the first time through depths of 10 mm using a handheld SORS instrument.
引用
收藏
页码:8530 / 8533
页数:4
相关论文
共 20 条
[1]   Extreme red shifted SERS nanotags [J].
Bedics, Matthew A. ;
Kearns, Hayleigh ;
Cox, Jordan M. ;
Mabbott, Sam ;
Ali, Fatima ;
Shand, Neil C. ;
Faulds, Karen ;
Benedict, Jason B. ;
Graham, Duncan ;
Detty, Michael R. .
CHEMICAL SCIENCE, 2015, 6 (04) :2302-2306
[2]   Actively Targeted In Vivo Multiplex Detection of Intrinsic Cancer Biomarkers Using Biocompatible SERS Nanotags [J].
Dinish, U. S. ;
Balasundaram, Ghayathri ;
Chang, Young-Tae ;
Olivo, Malini .
SCIENTIFIC REPORTS, 2014, 4
[3]   Through-container, extremely low concentration detection of multiple chemical markers of counterfeit alcohol using a handheld SORS device [J].
Ellis, David I. ;
Eccles, Rebecca ;
Xu, Yun ;
Griffen, Julia ;
Muhamadali, Howbeer ;
Matousek, Pavel ;
Goodall, Ian ;
Goodacre, Royston .
SCIENTIFIC REPORTS, 2017, 7
[4]   Surface-Enhanced Raman Spectroscopy Biosensing: In Vivo Diagnostics and Multimodal Imaging [J].
Henry, Anne-Isabelle ;
Sharma, Bhavya ;
Cardinal, M. Femanda ;
Kurouski, Dmitry ;
Van Duyne, Richard P. .
ANALYTICAL CHEMISTRY, 2016, 88 (13) :6638-6647
[5]   Targeted SERS nanosensors measure physicochemical gradients and free energy changes in live 3D tumor spheroids [J].
Jamieson, Lauren E. ;
Camus, Victoria L. ;
Bagnaninchi, Pierre O. ;
Fisher, Kate M. ;
Stewart, Grant D. ;
Nailon, William H. ;
McLaren, Duncan B. ;
Harrison, David J. ;
Campbell, Colin J. .
NANOSCALE, 2016, 8 (37) :16710-16718
[6]   SERS Detection of Multiple Antimicrobial-Resistant Pathogens Using Nanosensors [J].
Kearns, Hayleigh ;
Goodacre, Royston ;
Jamieson, Lauren E. ;
Graham, Duncan ;
Faulds, Karen .
ANALYTICAL CHEMISTRY, 2017, 89 (23) :12666-12673
[7]   In Vivo, Transcutaneous Glucose Sensing Using Surface-Enhanced Spatially Offset Raman Spectroscopy: Multiple Rats, Improved Hypoglycemic Accuracy, Low Incident Power, and Continuous Monitoring for Greater than 17 Days [J].
Ma, Ke ;
Yuen, Jonathan M. ;
Shah, Nilam C. ;
Walsh, Joseph T., Jr. ;
Glucksberg, Matthew R. ;
Van Duyne, Richard P. .
ANALYTICAL CHEMISTRY, 2011, 83 (23) :9146-9152
[8]   Surface Enhanced Spatially Offset Raman Spectroscopy Detection of Neurochemicals Through the Skull [J].
Moody, Amber S. ;
Baghernejad, Peymon C. ;
Webb, Kelsey R. ;
Sharma, Bhavya .
ANALYTICAL CHEMISTRY, 2017, 89 (11) :5689-5693
[9]   Through tissue imaging of a live breast cancer tumour model using handheld surface enhanced spatially offset resonance Raman spectroscopy (SESORRS) [J].
Nicolson, Fay ;
Jamieson, Lauren E. ;
Mabbott, Samuel ;
Plakas, Konstantinos ;
Shand, Neil C. ;
Detty, Michael R. ;
Graham, Duncan ;
Faulds, Karen .
CHEMICAL SCIENCE, 2018, 9 (15) :3788-3792
[10]   Through barrier detection of ethanol using handheld Raman spectroscopyConventional Raman versus spatially offset Raman spectroscopy (SORS) [J].
Nicolson, Fay ;
Jamieson, Lauren E. ;
Mabbott, Samuel ;
Shand, Neil C. ;
Graham, Duncan ;
Faulds, Karen .
JOURNAL OF RAMAN SPECTROSCOPY, 2017, 48 (12) :1828-1838