Aortic valve sclerosis in acute coronary syndrome patients Potential value in predicting coronary artery lesion complexity

被引：0

作者：

Korkmaz, L. ^{[1
]}

Pelit, E. ^{[1
]}

Bektas, H. ^{[1
]}

Agac, M. T. ^{[1
]}

Erkan, H. ^{[1
]}

Gurbak, I. ^{[1
]}

Celik, S. ^{[1
]}

机构：

[1] Ahi Evren Cardiovasc & Thorac Surg Training & Res, Dept Cardiol, Trabzon, Turkey

来源：

HERZ | 2014年 / 39卷 / 08期

关键词：

Aortic valve; Acute coronary syndrome; SYNTAX score; Ischemia; Risk assessment; ELEVATION MYOCARDIAL-INFARCTION; SYNTAX SCORE; INTERVENTION; DISEASE; RISK; EVENTS; STENT; DEATH; TRIAL; MI;

D O I：

10.1007/s00059-013-3936-6

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The purpose of the present study was to investigate the relation between aortic valve sclerosis (AVS) and coronary artery lesion complexity as assessed using the SYNTAX score (SxScore) in acute coronary syndrome (ACS) patients. A total of 164 patients with a first time diagnosis of acute coronary syndrome were consecutively enrolled. AVS was defined by echocardiography as thickening and calcification of the normal trileaflet aortic valve without obstruction to the left ventricular outflow. The SxScore was calculated using dedicated computer software. There were significantly higher SxScores in subjects with AVS than those without AVS (18 +/- 6 vs 12 +/- 5, p = 0.02). In the univariate analysis, age (p = 0.03) and presence of AVS (p = 0.007) were significantly associated with higher SxScores. Logistic regression analysis demonstrated AVS [95 % confidence interval (CI) 0.17-0.86, p = 0.017] and age (95 % CI 1.01-1.21, p = 0.028) as independent determinants of higher SxScores. Aortic valve sclerosis was significantly and independently associated with a high SxScore in acute coronary syndrome patients.

引用

页码：1001 / 1004

页数：4

共 19 条

[1] Minor myocardial damage and prognosis - Are spontaneous and percutaneous coronary intervention-related events different? [J].

Akkerhuis, KM ;

Alexander, JH ;

Tardiff, BE ;

Boersma, E ;

Harrington, RA ;

Lincoff, AM ;

Simoons, ML .

CIRCULATION, 2002, 105 (05) :554-556

[2] The TIMI risk score for unstable angina/non-ST elevation MI - A method for prognostication and therapeutic decision making [J].

Antman, EM ;

Cohen, M ;

Bernink, PJLM ;

McCabe, CH ;

Horacek, T ;

Papuchis, G ;

Mautner, B ;

Corbalan, R ;

Radley, D ;

Braunwald, E .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2000, 284 (07) :835-842

[3] Aortic valve sclerosis: A marker of significant obstructive coronary artery disease in patients with chest pain? [J].

Conte, Luca ;

Rossi, Andrea ;

Cicoira, Mariantonietta ;

Bonapace, Stefano ;

Amado, Eleas Alejandra ;

Golia, Giorgio ;

Zardini, Piero ;

Vassanelli, Corrado .

JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY, 2007, 20 (06) :703-708

[4] A validated prediction model for all forms of acute coronary syndrome - Estimating the risk of 6-month postdischarge death in an international registry [J].

Eagle, KA ;

Lim, MJ ;

Dabbous, OH ;

Pieper, KS ;

Goldberg, RJ ;

Van de Werf, F ;

Goodman, SG ;

Granger, CB ;

Steg, PG ;

Gore, JM ;

Budaj, A ;

Avezum, A ;

Flather, MD ;

Fox, KAA .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2004, 291 (22) :2727-2733

[5] Death following creatine kinase-MB elevation after coronary intervention - Identification of an early risk period: Importance of creatine kinase-MB level, completeness of revascularization, ventricular function, and probable benefit of statin therapy [J].

Ellis, SG ;

Chew, D ;

Chan, A ;

Whitlow, PL ;

Schneider, JP ;

Topol, EJ .

CIRCULATION, 2002, 106 (10) :1205-1210

[6] Spectrum of calcific aortic valve disease - Pathogenesis, disease progression, and treatment strategies [J].

Freeman, RV ;

Otto, CM .

CIRCULATION, 2005, 111 (24) :3316-3326

[7] Prediction of 1-Year Clinical Outcomes Using the SYNTAX Score in Patients With Acute ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention A Substudy of the STRATEGY (Single High-Dose Bolus Tirofiban and Sirolimus-Eluting Stent Versus Abciximab and Bare-Metal Stent in Acute Myocardial Infarction) and MULTISTRATEGY (Multicenter Evaluation of Single High-Dose Bolus Tirofiban Versus Abciximab With Sirolimus-Eluting Stent or Bare-Metal Stent in Acute Myocardial Infarction Study) Trials [J].

Garg, Scot ;

Sarno, Giovanna ;

Serruys, Patrick W. ;

Rodriguez, Alfredo E. ;

Bolognese, Leonardo ;

Anselmi, Maurizio ;

De Cesare, Nicoletta ;

Colangelo, Salvatore ;

Moreno, Raul ;

Gambetti, Stefania ;

Monti, Monia ;

Bristot, Laura ;

Bressers, Marco ;

Garcia-Garcia, Hector M. ;

Parrinello, Giovanni ;

Campo, Gianluca ;

Valgimigli, Marco .

JACC-CARDIOVASCULAR INTERVENTIONS, 2011, 4 (01) :66-75

[8]

Kim Dong-Bin, 2009, Korean Circ J, V39, P275, DOI 10.4070/kcj.2009.39.7.275

[9] Aortic knob calcification and coronary artery lesion complexity in non-ST-segment elevation acute coronary syndrome patients [J].

Korkmaz, Levent ;

Adar, Adem ;

Korkmaz, Ayca Ata ;

Erkan, Hakan ;

Agac, Mustafa Tarik ;

Acar, Zeydin ;

Akyuz, Ali Riza ;

Bektas, Huseyin ;

Celik, Sukru .

TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY, 2012, 40 (07) :606-611

[10] Clinical and Angiographic Predictors of Short- and Long-Term Ischemic Events in Acute Coronary Syndromes Results From the Acute Catheterization and Urgent Intervention Triage strategY (ACUITY) Trial [J].

Lansky, Alexandra J. ;

Goto, Kenji ;

Cristea, Ecaterina ;

Fahy, Martin ;

Parise, Helen ;

Feit, Frederick ;

Ohman, E. Magnus ;

White, Harvey D. ;

Alexander, Karen P. ;

Bertrand, Michel E. ;

Desmet, Walter ;

Hamon, Martial ;

Mehran, Roxana ;

Moses, Jeffrey ;

Leon, Martin ;

Stone, Gregg W. .

CIRCULATION-CARDIOVASCULAR INTERVENTIONS, 2010, 3 (04) :308-316

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