One-pot, three-component reaction of N-isocyanimino-triphenylphosphorane (Ph3PNNC), acenaphthoquinone, and an aromatic carboxylic acid in water

被引：7

作者：

Jafari, Ali ^{[1
]}

Ramazani, Ali ^{[1
]}

Sadri, Fariba ^{[2
]}

Joo, Sang Woo ^{[3
]}

机构：

[1] Univ Zanjan, Dept Chem, POB 45195-313, Zanjan, Iran

[2] Payame Noor Univ, Dept Chem, Tehran, Iran

[3] Yeungnam Univ, Sch Mech Engn, Kyongsan 712749, South Korea

来源：

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 2016年 / 191卷 / 02期

基金：

新加坡国家研究基金会;

关键词：

N-isocyanimino-triphenylphosphorane (Ph3PNNC); water; 1,3,4-oxadiazoles; aza-wittig reaction; aromatic carboxylic acid; EFFICIENT ONE-POT; SUBSTITUTED 1,3,4-OXADIAZOLE DERIVATIVES; CATALYZED STEREOSELECTIVE CONVERSION; 4-COMPONENT SYNTHESIS; MULTICOMPONENT REACTIONS; DISUBSTITUTED 1,3,4-OXADIAZOLES; (E)-CINNAMIC ACIDS; SECONDARY AMINE; SILICA-GEL; PHENYLACETYLENECARBOXYLIC ACID;

D O I：

10.1080/10426507.2015.1054933

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Water was used as an efficient green solvent for the synthesis of sterically congested 1,3,4-oxadiazoles derivatives via a one-pot, three-component reaction of various aromatic carboxylic acids, acenaphthoquinone, and N-isocyanimino-triphenylphosphorane (Ph3PNNC) at a reaction temperature of 20-26 degrees C for 15h. The remarkable features of this green methodology include high yield of products, water as the solvent, short reaction time, operational simplicity, environmentally benign, and the absence of any volatile or hazardous organic solvents.

引用

页码：316 / 321

页数：6

共 70 条

[1] THE REACTION OF N-ISOCYANIMINOTRIPHENYLPHOSPHORANE WITH CYCLOPENTANONE AND A PRIMARY AMINE IN THE PRESENCE OF AN E-CINNAMIC ACID DERIVATIVE [J].