Polyfunctional Zinc and Magnesium Organometallics for Organic Synthesis: Some Perspectives

被引：51

作者：

Benischke, Andreas D. ^{[1
]}

Ellwart, Mario ^{[1
]}

Becker, Matthias R. ^{[1
]}

Knochel, Paul ^{[1
]}

机构：

[1] Univ Munich, Dept Chem, Butenandtstr 5-13, D-81377 Munich, Germany

来源：

SYNTHESIS-STUTTGART | 2016年 / 48卷 / 08期

关键词：

zinc; magnesium; lithium chloride; flow chemistry; Lewis acids; FRUSTRATED LEWIS PAIRS; FUNCTIONALIZED ORGANOZINC COMPOUNDS; HIGHLY SELECTIVE METALATIONS; LITHIUM-MEDIATED ZINCATION; CATALYZED CROSS-COUPLINGS; CONTINUOUS-FLOW SYNTHESIS; ACIDIC HYDROGEN-ATOMS; MIXED AGGREGATE MAA; CENTER-DOT-LICL; DEPROTONATIVE METALATION;

D O I：

10.1055/s-0035-1561198

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The most important methods for the preparation of polyfunctional Zn and Mg reagents are highlighted. New perspectives for increasing the synthetic potential of these reagents including the use of Lewis acid catalysis, in situ trapping reactions, continuous flow conditions, and solid, air-stable zinc organometallics are described.

引用

页码：1101 / 1107

页数：7

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