Synthesis of Structurally Diverse Allylsilanes via Copper-Catalyzed Regiodivergent Hydrosilylation of 1,3-Dienes

被引：32

作者：

Wang, Zi-Lu ^{[1
,2
]}

Wang, Ying ^{[1
,2
]}

Xu, Jian-Lin ^{[1
,2
]}

Zhao, Meng ^{[1
,2
]}

Dai, Kai-Yang ^{[1
,2
]}

Shan, Cui-Cui ^{[1
,2
]}

Xu, Yun-He ^{[1
,2
,3
,4
]}

机构：

[1] Univ Sci & Technol China, Dept Chem, Hefei 230026, Peoples R China

[2] Univ Sci & Technol China, Hefei Natl Lab Phys Sci Microscale, Hefei 230026, Peoples R China

[3] Nankai Univ, State Key Lab, Tianjin 300071, Peoples R China

[4] Nankai Univ, Inst Elementoorgan Chem, Tianjin 300071, Peoples R China

来源：

ORGANIC LETTERS | 2021年 / 23卷 / 12期

基金：

中国国家自然科学基金;

关键词：

ASYMMETRIC HYDROSILYLATION; SILICON; ACTIVATION; STEREOCHEMISTRY; SILYLATION; MECHANISM; REAGENTS;

D O I：

10.1021/acs.orglett.1c01455

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Unprecedented copper-catalyzed regiodivergent hydrosilylation reactions of substituted 1,3-dienes with hydrosilanes have been developed. The 1,2- and 1,4-hydrosilylations of 1-(hetero)aryl-substituted 1,3-dienes were highly selectively controlled via variation of the catalytic systems. Meanwhile, the 1,4-hydrosilylation reaction of 2-aryl-substituted 1,3-dienes with diphenylsilane was also successfully realized for the first time. These methods provide convenient and efficient approaches for the synthesis of structurally diverse allylsilanes.

引用

页码：4736 / 4742

页数：7

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