Idiopathic hypoparathyroidism (IH) and autoimmune pulmonary alveolar proteinosis (PAP) are rare disorders. A patient with IH and optimal calcaemic control on calcium and alfacalcidol was detected to have PAP after 8 years of follow-up. Patient had no respiratory complaints. Routine abdominal imaging for renal calcification showed patchy ground glass opacities in the lower lung fields leading to incidental diagnosis of PAP. Pulmonary function tests showed impaired diffusion capacity of the lung. Anti-granulocyte macrophage-colony stimulating factor autoantibodies were positive. Patient regularly attended the pulmonary clinic and showed progressive improvement in diffusion capacity of the lung during 2 years of follow-up. The calcaemic control in IH remained stable despite its presence with PAP. The autoimmune PAP in the presented case suggests a possible autoimmune basis of IH.
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Univ Calif San Diego Hlth Syst, Div Pulm Crit Care Sleep Med & Physiol, San Diego, CA USAUniv Calif San Diego Hlth Syst, Div Pulm Crit Care Sleep Med & Physiol, San Diego, CA USA
Lee, Dabin
Cho, Gene
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Univ Calif San Diego, La Jolla, CA USAUniv Calif San Diego Hlth Syst, Div Pulm Crit Care Sleep Med & Physiol, San Diego, CA USA
Cho, Gene
Matti, Moreen
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Univ Calif San Diego, La Jolla, CA USA
Univ Calif San Diego, San Diego, La Jolla, CA 92093 USAUniv Calif San Diego Hlth Syst, Div Pulm Crit Care Sleep Med & Physiol, San Diego, CA USA
Matti, Moreen
Nobari, Matthew
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Univ Calif San Diego Hlth Syst, Div Pulm Crit Care Sleep Med & Physiol, San Diego, CA USAUniv Calif San Diego Hlth Syst, Div Pulm Crit Care Sleep Med & Physiol, San Diego, CA USA
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King Faisal Specialist Hosp & Res Ctr, Lung Hlth Ctr, Organ Transplant Ctr Excellence, Riyadh, Saudi Arabia
Alfaisal Univ, Coll Med, Riyadh, Saudi ArabiaKing Faisal Specialist Hosp & Res Ctr, Lung Hlth Ctr, Organ Transplant Ctr Excellence, Riyadh, Saudi Arabia
Abdulqawi, Rayid
Alsaif, Janat
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King Fahad Specialist Hosp Dammam, Dept Med, Dammam, Saudi ArabiaKing Faisal Specialist Hosp & Res Ctr, Lung Hlth Ctr, Organ Transplant Ctr Excellence, Riyadh, Saudi Arabia
Alsaif, Janat
Ismail, Huda
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King Fahad Specialist Hosp Dammam, Med Imaging Dept, Dammam, Saudi ArabiaKing Faisal Specialist Hosp & Res Ctr, Lung Hlth Ctr, Organ Transplant Ctr Excellence, Riyadh, Saudi Arabia
Ismail, Huda
Aljishi, Ahmed
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King Fahad Specialist Hosp Dammam, Dept Med, Dammam, Saudi ArabiaKing Faisal Specialist Hosp & Res Ctr, Lung Hlth Ctr, Organ Transplant Ctr Excellence, Riyadh, Saudi Arabia