Aggravation of seizures and status epilepticus after vagal nerve stimulation therapy: the first pediatric case and review of the literature

被引：6

作者：

Arhan, Ebru ^{[1
,2
]}

Serdaroglu, Ayse ^{[1
]}

Hirfanoglu, Tugba ^{[1
]}

Kurt, Gokhan ^{[3
]}

机构：

[1] Gazi Univ, Dept Pediat Neurol, Sch Med, Ankara, Turkey

[2] Gazi Univ, Pediat Neurol Dept, Fac Med, 10 Th Floor Besevler, Ankara, Turkey

[3] Gazi Univ, Dept Neurosurg, Sch Med, Ankara, Turkey

来源：

CHILDS NERVOUS SYSTEM | 2018年 / 34卷 / 09期

关键词：

Epilepsy; Seizures; Vagal nerve stimulation; EPILEPSY;

D O I：

10.1007/s00381-018-3806-x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A 13-year-old girl presented with refractory secondary generalized focal epilepsy. Vagal nerve stimulator was implanted because of drug-resistant epilepsy. After the increase of vagal nerve stimulator current output to a relatively high level, the patient experienced seizure aggravation and status epilepticus. We conclude that vagus nerve stimulation may induce paradoxical seizures and may lead to status epilepticus, similarly to some antiepileptic drugs.

引用

页码：1799 / 1801

页数：3

共 7 条

[1] Investigation into the mechanisms of vagus nerve stimulation for the treatment of intractable epilepsy, using 99mTc-HMPAO SPET brain images [J].

Barnes, A ;

Duncan, R ;

Chisholm, JA ;

Lindsay, K ;

Patterson, J ;

Wyper, D .

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2003, 30 (02) :301-305

[2] Aggravation of partial epilepsy and emergence of new seizure type during treatment with VNS [J].

Koutroumanidis, M ;

Hennessy, MJ ;

Binnie, CD ;

Polkey, CE .

NEUROLOGY, 2000, 55 (06) :892-893

[3]

Krahl Scott E, 2012, Surg Neurol Int, V3, pS255, DOI 10.4103/2152-7806.103015

[4] Long-term treatment with vague nerve stimulation in patients with refractory epilepsy [J].

Morris, GL ;

Mueller, WM .

NEUROLOGY, 1999, 53 (08) :1731-1735

[5] Severe new seizures after initiation of vagus nerve stimulation therapy [J].

Murr, Najib I. ;

Azar, Nabil J. .

EPILEPSY & BEHAVIOR, 2011, 22 (02) :398-400

[6] ANATOMICAL, PHYSIOLOGICAL, AND THEORETICAL BASIS FOR THE ANTIEPILEPTIC EFFECT OF VAGUS NERVE-STIMULATION [J].

RUTECKI, P .

EPILEPSIA, 1990, 31 :S1-S6

[7] A PROGRESSIVE SEQUENCE OF ELECTROENCEPHALOGRAPHIC CHANGES DURING GENERALIZED CONVULSIVE STATUS EPILEPTICUS [J].

TREIMAN, DM ;

WALTON, NY ;

KENDRICK, C .

EPILEPSY RESEARCH, 1990, 5 (01) :49-60

← 1 →