Fluorescent nanocrystal quantum dots (QDs) have the potential to be applied to bioimaging since QDs emit higher and far longer fluorescence than conventional organic probes. Here we show that QDs conjugated with signal peptide obey the order to transport the assigned organelle in living cells. We designed the supermolecule of luminescent QDs conjugated with nuclear- and mitochondria-targeting ligands. When QDs with nuclear-localizing signal peptides were added to the culture media, we can visualize the movements of the QDs being delivered into the nuclear compartment of the cells with 15 min incubation. In addition, mitochondrial signal peptide can also transport QDs to the mitochondria in living cells. In conclusion, these techniques have the possibility that QDs can reveal the transduction of proteins and peptides into specific subcellular compartments as a powerful tool for studying intracellular analysis in vitro and even in vivo.
机构:Qingdao University of Science and Technology,Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, Shandong Key Laboratory of Biochemical Analysis, Key Laboratory of Analytical Chemistry for Life Science in Universities of Shandong, Col
Zhi-Ling Song
Xin Dai
论文数: 0引用数: 0
h-index: 0
机构:Qingdao University of Science and Technology,Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, Shandong Key Laboratory of Biochemical Analysis, Key Laboratory of Analytical Chemistry for Life Science in Universities of Shandong, Col
Xin Dai
Mengru Li
论文数: 0引用数: 0
h-index: 0
机构:Qingdao University of Science and Technology,Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, Shandong Key Laboratory of Biochemical Analysis, Key Laboratory of Analytical Chemistry for Life Science in Universities of Shandong, Col
Mengru Li
He Teng
论文数: 0引用数: 0
h-index: 0
机构:Qingdao University of Science and Technology,Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, Shandong Key Laboratory of Biochemical Analysis, Key Laboratory of Analytical Chemistry for Life Science in Universities of Shandong, Col
He Teng
Zhen Song
论文数: 0引用数: 0
h-index: 0
机构:Qingdao University of Science and Technology,Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, Shandong Key Laboratory of Biochemical Analysis, Key Laboratory of Analytical Chemistry for Life Science in Universities of Shandong, Col
Zhen Song
Dexun Xie
论文数: 0引用数: 0
h-index: 0
机构:Qingdao University of Science and Technology,Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, Shandong Key Laboratory of Biochemical Analysis, Key Laboratory of Analytical Chemistry for Life Science in Universities of Shandong, Col
Dexun Xie
Xiliang Luo
论文数: 0引用数: 0
h-index: 0
机构:Qingdao University of Science and Technology,Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, Shandong Key Laboratory of Biochemical Analysis, Key Laboratory of Analytical Chemistry for Life Science in Universities of Shandong, Col
机构:
Catholic Univ Korea, Dept Internal Med, Seoul 137701, South Korea
Catholic Univ Korea, WHO Collaborating Ctr Viral Hepatitis, Seoul 137701, South KoreaCatholic Univ Korea, Dept Internal Med, Seoul 137701, South Korea
Hur, Wonhee
Park, Sang-Jun
论文数: 0引用数: 0
h-index: 0
机构:
Pohang Univ Sci & Technol POSTECH, Dept Mat Sci & Engn, Pohang 790784, Kyungbuk, South KoreaCatholic Univ Korea, Dept Internal Med, Seoul 137701, South Korea
Park, Sang-Jun
论文数: 引用数:
h-index:
机构:
Hong, Sung Woo
论文数: 引用数:
h-index:
机构:
Choi, Jung Eun
Goh, Eun Ji
论文数: 0引用数: 0
h-index: 0
机构:
Pohang Univ Sci & Technol POSTECH, Dept Mat Sci & Engn, Pohang 790784, Kyungbuk, South KoreaCatholic Univ Korea, Dept Internal Med, Seoul 137701, South Korea
机构:
Wuhan Univ, Dept Gynecol, Renmin Hosp, Wuhan 430060, Hubei, Peoples R China
Wuhan Univ, Sch Pharmaceut Sci, Minist Educ, Key Lab Combinatorial Biosynth & Drug Discovery, Wuhan 430071, Peoples R China
Korea Univ, Dept Chem, Seoul 02841, South KoreaWuhan Univ, Dept Gynecol, Renmin Hosp, Wuhan 430060, Hubei, Peoples R China
Ding, Qihang
Luo, Yan
论文数: 0引用数: 0
h-index: 0
机构:
Wuhan Univ, Dept Gynecol, Renmin Hosp, Wuhan 430060, Hubei, Peoples R ChinaWuhan Univ, Dept Gynecol, Renmin Hosp, Wuhan 430060, Hubei, Peoples R China
Luo, Yan
Hu, Jun
论文数: 0引用数: 0
h-index: 0
机构:
Wuhan Univ, Demonstrat Ctr Expt Basic Med Educ, Sch Basic Med Sci, Wuhan 430071, Hubei, Peoples R ChinaWuhan Univ, Dept Gynecol, Renmin Hosp, Wuhan 430060, Hubei, Peoples R China
Hu, Jun
Zhang, Shuai
论文数: 0引用数: 0
h-index: 0
机构:
Harbin Med Univ, Canc Hosp, Dept Med Oncol, 150 Haping Rd, Harbin 150040, Heilongjiang, Peoples R ChinaWuhan Univ, Dept Gynecol, Renmin Hosp, Wuhan 430060, Hubei, Peoples R China
Zhang, Shuai
Zhang, Wenzhe
论文数: 0引用数: 0
h-index: 0
机构:
Wuhan Univ, Dept Gynecol, Renmin Hosp, Wuhan 430060, Hubei, Peoples R China
Wuhan Univ, Sch Pharmaceut Sci, Minist Educ, Key Lab Combinatorial Biosynth & Drug Discovery, Wuhan 430071, Peoples R ChinaWuhan Univ, Dept Gynecol, Renmin Hosp, Wuhan 430060, Hubei, Peoples R China
Zhang, Wenzhe
Feng, Yuanyuan
论文数: 0引用数: 0
h-index: 0
机构:
Wuhan Univ, Dept Gynecol, Renmin Hosp, Wuhan 430060, Hubei, Peoples R China
Wuhan Univ, Sch Pharmaceut Sci, Minist Educ, Key Lab Combinatorial Biosynth & Drug Discovery, Wuhan 430071, Peoples R ChinaWuhan Univ, Dept Gynecol, Renmin Hosp, Wuhan 430060, Hubei, Peoples R China
Feng, Yuanyuan
Qian, Kun
论文数: 0引用数: 0
h-index: 0
机构:
Chinese Acad Sci, Shanghai Inst Mat Med, Mol Imaging Ctr, State Key Lab Drug Res, Shanghai 201203, Peoples R ChinaWuhan Univ, Dept Gynecol, Renmin Hosp, Wuhan 430060, Hubei, Peoples R China
Qian, Kun
Li, Xin
论文数: 0引用数: 0
h-index: 0
机构:
Wuhan Univ, Dept Gynecol, Renmin Hosp, Wuhan 430060, Hubei, Peoples R ChinaWuhan Univ, Dept Gynecol, Renmin Hosp, Wuhan 430060, Hubei, Peoples R China
Li, Xin
Cheng, Zhen
论文数: 0引用数: 0
h-index: 0
机构:
Chinese Acad Sci, Shanghai Inst Mat Med, Mol Imaging Ctr, State Key Lab Drug Res, Shanghai 201203, Peoples R China
Bohai Rim Adv Res Inst Drug Discovery, Shandong Lab Yantai Drug Discovery, Yantai 264117, Shandong, Peoples R ChinaWuhan Univ, Dept Gynecol, Renmin Hosp, Wuhan 430060, Hubei, Peoples R China
Cheng, Zhen
Gu, Meijia
论文数: 0引用数: 0
h-index: 0
机构:
Wuhan Univ, Dept Gynecol, Renmin Hosp, Wuhan 430060, Hubei, Peoples R China
Wuhan Univ, Sch Pharmaceut Sci, Minist Educ, Key Lab Combinatorial Biosynth & Drug Discovery, Wuhan 430071, Peoples R ChinaWuhan Univ, Dept Gynecol, Renmin Hosp, Wuhan 430060, Hubei, Peoples R China
机构:
BAM Fed Inst Mat Res & Testing, Div Biophoton, Richard Willstaetter Str 11, D-12489 Berlin, GermanyBAM Fed Inst Mat Res & Testing, Div Biophoton, Richard Willstaetter Str 11, D-12489 Berlin, Germany
Wegner, K. David
Resch-Genger, Ute
论文数: 0引用数: 0
h-index: 0
机构:
BAM Fed Inst Mat Res & Testing, Div Biophoton, Richard Willstaetter Str 11, D-12489 Berlin, GermanyBAM Fed Inst Mat Res & Testing, Div Biophoton, Richard Willstaetter Str 11, D-12489 Berlin, Germany
机构:
Univ Fed Pernambuco, Dept Chem Engn, Cidade Univ,Ave Prof Artur de Sa S-N, BR-50740521 Recife, PE, BrazilUniv Fed Pernambuco, Dept Chem Engn, Cidade Univ,Ave Prof Artur de Sa S-N, BR-50740521 Recife, PE, Brazil
do Nascimento, Aquiles Silva
Costa Ferrer, Nadson Humberto
论文数: 0引用数: 0
h-index: 0
机构:
Univ Fed Pernambuco, Dept Chem Engn, Cidade Univ,Ave Prof Artur de Sa S-N, BR-50740521 Recife, PE, BrazilUniv Fed Pernambuco, Dept Chem Engn, Cidade Univ,Ave Prof Artur de Sa S-N, BR-50740521 Recife, PE, Brazil
Costa Ferrer, Nadson Humberto
Melo, Vitor Davis
论文数: 0引用数: 0
h-index: 0
机构:
Univ Fed Pernambuco, Dept Chem Engn, Cidade Univ,Ave Prof Artur de Sa S-N, BR-50740521 Recife, PE, BrazilUniv Fed Pernambuco, Dept Chem Engn, Cidade Univ,Ave Prof Artur de Sa S-N, BR-50740521 Recife, PE, Brazil
Melo, Vitor Davis
Fontes, Adriana
论文数: 0引用数: 0
h-index: 0
机构:
Univ Fed Pernambuco, Dept Biophys & Radiobiol, Ave Prof Moraes Rego 1235, BR-50670901 Recife, PE, BrazilUniv Fed Pernambuco, Dept Chem Engn, Cidade Univ,Ave Prof Artur de Sa S-N, BR-50740521 Recife, PE, Brazil
Fontes, Adriana
Santos, Beate Saegesser
论文数: 0引用数: 0
h-index: 0
机构:
Univ Fed Pernambuco, Dept Pharmaceut Sci, Ave Prof Artur de Sa S-N, BR-50740520 Recife, PE, BrazilUniv Fed Pernambuco, Dept Chem Engn, Cidade Univ,Ave Prof Artur de Sa S-N, BR-50740521 Recife, PE, Brazil
Santos, Beate Saegesser
Stragevitch, Luiz
论文数: 0引用数: 0
h-index: 0
机构:
Univ Fed Pernambuco, Dept Chem Engn, Cidade Univ,Ave Prof Artur de Sa S-N, BR-50740521 Recife, PE, BrazilUniv Fed Pernambuco, Dept Chem Engn, Cidade Univ,Ave Prof Artur de Sa S-N, BR-50740521 Recife, PE, Brazil
Stragevitch, Luiz
Leite, Elisa Soares
论文数: 0引用数: 0
h-index: 0
机构:
Univ Fed Pernambuco, Dept Chem Engn, Cidade Univ,Ave Prof Artur de Sa S-N, BR-50740521 Recife, PE, BrazilUniv Fed Pernambuco, Dept Chem Engn, Cidade Univ,Ave Prof Artur de Sa S-N, BR-50740521 Recife, PE, Brazil
机构:Qingdao University of Science and Technology,Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, Shandong Key Laboratory of Biochemical Analysis, Key Laboratory of Analytical Chemistry for Life Science in Universities of Shandong, Col
Zhi-Ling Song
Xin Dai
论文数: 0引用数: 0
h-index: 0
机构:Qingdao University of Science and Technology,Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, Shandong Key Laboratory of Biochemical Analysis, Key Laboratory of Analytical Chemistry for Life Science in Universities of Shandong, Col
Xin Dai
Mengru Li
论文数: 0引用数: 0
h-index: 0
机构:Qingdao University of Science and Technology,Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, Shandong Key Laboratory of Biochemical Analysis, Key Laboratory of Analytical Chemistry for Life Science in Universities of Shandong, Col
Mengru Li
He Teng
论文数: 0引用数: 0
h-index: 0
机构:Qingdao University of Science and Technology,Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, Shandong Key Laboratory of Biochemical Analysis, Key Laboratory of Analytical Chemistry for Life Science in Universities of Shandong, Col
He Teng
Zhen Song
论文数: 0引用数: 0
h-index: 0
机构:Qingdao University of Science and Technology,Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, Shandong Key Laboratory of Biochemical Analysis, Key Laboratory of Analytical Chemistry for Life Science in Universities of Shandong, Col
Zhen Song
Dexun Xie
论文数: 0引用数: 0
h-index: 0
机构:Qingdao University of Science and Technology,Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, Shandong Key Laboratory of Biochemical Analysis, Key Laboratory of Analytical Chemistry for Life Science in Universities of Shandong, Col
Dexun Xie
Xiliang Luo
论文数: 0引用数: 0
h-index: 0
机构:Qingdao University of Science and Technology,Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, Shandong Key Laboratory of Biochemical Analysis, Key Laboratory of Analytical Chemistry for Life Science in Universities of Shandong, Col
机构:
Catholic Univ Korea, Dept Internal Med, Seoul 137701, South Korea
Catholic Univ Korea, WHO Collaborating Ctr Viral Hepatitis, Seoul 137701, South KoreaCatholic Univ Korea, Dept Internal Med, Seoul 137701, South Korea
Hur, Wonhee
Park, Sang-Jun
论文数: 0引用数: 0
h-index: 0
机构:
Pohang Univ Sci & Technol POSTECH, Dept Mat Sci & Engn, Pohang 790784, Kyungbuk, South KoreaCatholic Univ Korea, Dept Internal Med, Seoul 137701, South Korea
Park, Sang-Jun
论文数: 引用数:
h-index:
机构:
Hong, Sung Woo
论文数: 引用数:
h-index:
机构:
Choi, Jung Eun
Goh, Eun Ji
论文数: 0引用数: 0
h-index: 0
机构:
Pohang Univ Sci & Technol POSTECH, Dept Mat Sci & Engn, Pohang 790784, Kyungbuk, South KoreaCatholic Univ Korea, Dept Internal Med, Seoul 137701, South Korea
机构:
Wuhan Univ, Dept Gynecol, Renmin Hosp, Wuhan 430060, Hubei, Peoples R China
Wuhan Univ, Sch Pharmaceut Sci, Minist Educ, Key Lab Combinatorial Biosynth & Drug Discovery, Wuhan 430071, Peoples R China
Korea Univ, Dept Chem, Seoul 02841, South KoreaWuhan Univ, Dept Gynecol, Renmin Hosp, Wuhan 430060, Hubei, Peoples R China
Ding, Qihang
Luo, Yan
论文数: 0引用数: 0
h-index: 0
机构:
Wuhan Univ, Dept Gynecol, Renmin Hosp, Wuhan 430060, Hubei, Peoples R ChinaWuhan Univ, Dept Gynecol, Renmin Hosp, Wuhan 430060, Hubei, Peoples R China
Luo, Yan
Hu, Jun
论文数: 0引用数: 0
h-index: 0
机构:
Wuhan Univ, Demonstrat Ctr Expt Basic Med Educ, Sch Basic Med Sci, Wuhan 430071, Hubei, Peoples R ChinaWuhan Univ, Dept Gynecol, Renmin Hosp, Wuhan 430060, Hubei, Peoples R China
Hu, Jun
Zhang, Shuai
论文数: 0引用数: 0
h-index: 0
机构:
Harbin Med Univ, Canc Hosp, Dept Med Oncol, 150 Haping Rd, Harbin 150040, Heilongjiang, Peoples R ChinaWuhan Univ, Dept Gynecol, Renmin Hosp, Wuhan 430060, Hubei, Peoples R China
Zhang, Shuai
Zhang, Wenzhe
论文数: 0引用数: 0
h-index: 0
机构:
Wuhan Univ, Dept Gynecol, Renmin Hosp, Wuhan 430060, Hubei, Peoples R China
Wuhan Univ, Sch Pharmaceut Sci, Minist Educ, Key Lab Combinatorial Biosynth & Drug Discovery, Wuhan 430071, Peoples R ChinaWuhan Univ, Dept Gynecol, Renmin Hosp, Wuhan 430060, Hubei, Peoples R China
Zhang, Wenzhe
Feng, Yuanyuan
论文数: 0引用数: 0
h-index: 0
机构:
Wuhan Univ, Dept Gynecol, Renmin Hosp, Wuhan 430060, Hubei, Peoples R China
Wuhan Univ, Sch Pharmaceut Sci, Minist Educ, Key Lab Combinatorial Biosynth & Drug Discovery, Wuhan 430071, Peoples R ChinaWuhan Univ, Dept Gynecol, Renmin Hosp, Wuhan 430060, Hubei, Peoples R China
Feng, Yuanyuan
Qian, Kun
论文数: 0引用数: 0
h-index: 0
机构:
Chinese Acad Sci, Shanghai Inst Mat Med, Mol Imaging Ctr, State Key Lab Drug Res, Shanghai 201203, Peoples R ChinaWuhan Univ, Dept Gynecol, Renmin Hosp, Wuhan 430060, Hubei, Peoples R China
Qian, Kun
Li, Xin
论文数: 0引用数: 0
h-index: 0
机构:
Wuhan Univ, Dept Gynecol, Renmin Hosp, Wuhan 430060, Hubei, Peoples R ChinaWuhan Univ, Dept Gynecol, Renmin Hosp, Wuhan 430060, Hubei, Peoples R China
Li, Xin
Cheng, Zhen
论文数: 0引用数: 0
h-index: 0
机构:
Chinese Acad Sci, Shanghai Inst Mat Med, Mol Imaging Ctr, State Key Lab Drug Res, Shanghai 201203, Peoples R China
Bohai Rim Adv Res Inst Drug Discovery, Shandong Lab Yantai Drug Discovery, Yantai 264117, Shandong, Peoples R ChinaWuhan Univ, Dept Gynecol, Renmin Hosp, Wuhan 430060, Hubei, Peoples R China
Cheng, Zhen
Gu, Meijia
论文数: 0引用数: 0
h-index: 0
机构:
Wuhan Univ, Dept Gynecol, Renmin Hosp, Wuhan 430060, Hubei, Peoples R China
Wuhan Univ, Sch Pharmaceut Sci, Minist Educ, Key Lab Combinatorial Biosynth & Drug Discovery, Wuhan 430071, Peoples R ChinaWuhan Univ, Dept Gynecol, Renmin Hosp, Wuhan 430060, Hubei, Peoples R China
机构:
BAM Fed Inst Mat Res & Testing, Div Biophoton, Richard Willstaetter Str 11, D-12489 Berlin, GermanyBAM Fed Inst Mat Res & Testing, Div Biophoton, Richard Willstaetter Str 11, D-12489 Berlin, Germany
Wegner, K. David
Resch-Genger, Ute
论文数: 0引用数: 0
h-index: 0
机构:
BAM Fed Inst Mat Res & Testing, Div Biophoton, Richard Willstaetter Str 11, D-12489 Berlin, GermanyBAM Fed Inst Mat Res & Testing, Div Biophoton, Richard Willstaetter Str 11, D-12489 Berlin, Germany
机构:
Univ Fed Pernambuco, Dept Chem Engn, Cidade Univ,Ave Prof Artur de Sa S-N, BR-50740521 Recife, PE, BrazilUniv Fed Pernambuco, Dept Chem Engn, Cidade Univ,Ave Prof Artur de Sa S-N, BR-50740521 Recife, PE, Brazil
do Nascimento, Aquiles Silva
Costa Ferrer, Nadson Humberto
论文数: 0引用数: 0
h-index: 0
机构:
Univ Fed Pernambuco, Dept Chem Engn, Cidade Univ,Ave Prof Artur de Sa S-N, BR-50740521 Recife, PE, BrazilUniv Fed Pernambuco, Dept Chem Engn, Cidade Univ,Ave Prof Artur de Sa S-N, BR-50740521 Recife, PE, Brazil
Costa Ferrer, Nadson Humberto
Melo, Vitor Davis
论文数: 0引用数: 0
h-index: 0
机构:
Univ Fed Pernambuco, Dept Chem Engn, Cidade Univ,Ave Prof Artur de Sa S-N, BR-50740521 Recife, PE, BrazilUniv Fed Pernambuco, Dept Chem Engn, Cidade Univ,Ave Prof Artur de Sa S-N, BR-50740521 Recife, PE, Brazil
Melo, Vitor Davis
Fontes, Adriana
论文数: 0引用数: 0
h-index: 0
机构:
Univ Fed Pernambuco, Dept Biophys & Radiobiol, Ave Prof Moraes Rego 1235, BR-50670901 Recife, PE, BrazilUniv Fed Pernambuco, Dept Chem Engn, Cidade Univ,Ave Prof Artur de Sa S-N, BR-50740521 Recife, PE, Brazil
Fontes, Adriana
Santos, Beate Saegesser
论文数: 0引用数: 0
h-index: 0
机构:
Univ Fed Pernambuco, Dept Pharmaceut Sci, Ave Prof Artur de Sa S-N, BR-50740520 Recife, PE, BrazilUniv Fed Pernambuco, Dept Chem Engn, Cidade Univ,Ave Prof Artur de Sa S-N, BR-50740521 Recife, PE, Brazil
Santos, Beate Saegesser
Stragevitch, Luiz
论文数: 0引用数: 0
h-index: 0
机构:
Univ Fed Pernambuco, Dept Chem Engn, Cidade Univ,Ave Prof Artur de Sa S-N, BR-50740521 Recife, PE, BrazilUniv Fed Pernambuco, Dept Chem Engn, Cidade Univ,Ave Prof Artur de Sa S-N, BR-50740521 Recife, PE, Brazil
Stragevitch, Luiz
Leite, Elisa Soares
论文数: 0引用数: 0
h-index: 0
机构:
Univ Fed Pernambuco, Dept Chem Engn, Cidade Univ,Ave Prof Artur de Sa S-N, BR-50740521 Recife, PE, BrazilUniv Fed Pernambuco, Dept Chem Engn, Cidade Univ,Ave Prof Artur de Sa S-N, BR-50740521 Recife, PE, Brazil