A Review on Metal- and Metal Oxide-Based Nanozymes: Properties, Mechanisms, and Applications

被引：485

作者：

Liu, Qianwen ^{[1
,2
]}

Zhang, Amin ^{[1
,2
]}

Wang, Ruhao ^{[1
,2
]}

Zhang, Qian ^{[1
,2
]}

Cui, Daxiang ^{[1
,2
]}

机构：

[1] Shanghai Jiao Tong Univ, Sch Elect Informat & Elect Engn, Shanghai Engn Res Ctr Intelligent Diag & Treatmen, Inst Nano Biomed & Engn,Dept Instrument Sci Engn, 800 Dongchuan RD, Shanghai 200240, Peoples R China

[2] Natl Engn Res Ctr Nanotechnol, Inst Nano Biomed, 28 Jiangchuan Easternroad, Shanghai 200241, Peoples R China

来源：

NANO-MICRO LETTERS | 2021年 / 13卷 / 01期

基金：

中国博士后科学基金;

关键词：

Metal- and metal oxide-based nanozymes; Intrinsic properties; Catalytic mechanism; Applications; PEROXIDASE-LIKE ACTIVITY; SENSITIVE COLORIMETRIC DETECTION; FUNCTIONALIZED GOLD NANOPARTICLES; ENZYME-LIKE ACTIVITY; CORE-SHELL NANOCOMPOSITES; HIGHLY-ACTIVE PEROXIDASE; IN-SITU SYNTHESIS; HYDROGEN-PEROXIDE; CATALYTIC-ACTIVITY; BIMETALLIC NANOPARTICLES;

D O I：

10.1007/s40820-021-00674-8

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Since the ferromagnetic (Fe3O4) nanoparticles were firstly reported to exert enzyme-like activity in 2007, extensive research progress in nanozymes has been made with deep investigation of diverse nanozymes and rapid development of related nanotechnologies. As promising alternatives for natural enzymes, nanozymes have broadened the way toward clinical medicine, food safety, environmental monitoring, and chemical production. The past decade has witnessed the rapid development of metal- and metal oxide-based nanozymes owing to their remarkable physicochemical properties in parallel with low cost, high stability, and easy storage. It is widely known that the deep study of catalytic activities and mechanism sheds significant influence on the applications of nanozymes. This review digs into the characteristics and intrinsic properties of metal- and metal oxide-based nanozymes, especially emphasizing their catalytic mechanism and recent applications in biological analysis, relieving inflammation, antibacterial, and cancer therapy. We also conclude the present challenges and provide insights into the future research of nanozymes constituted of metal and metal oxide nanomaterials.

引用

页数：53

共 435 条

[1] Recent Progress in Cancer Thermal Therapy Using Gold Nanoparticles [J].