(5S)-1-aza-2-imino-3-oxa-4,4-diphenylbicyclo(3.3.0)octane:: a novel chiral catalytic source containing the N-(C=NH)-O moiety for the borane-mediated asymmetric reduction of prochiral ketones

被引：6

作者：

Basavaiah, Deevi ^{[1
]}

Rao, Kalapala Venkateswara ^{[1
]}

Reddy, Bhavanam Sekhara ^{[1
]}

机构：

[1] Univ Hyderabad, Sch Chem, Hyderabad 500046, Andhra Pradesh, India

来源：

TETRAHEDRON-ASYMMETRY | 2007年 / 18卷 / 08期

关键词：

D O I：

10.1016/j.tetasy.2007.03.017

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

(5S)- 1-Aza-2-imino-3-oxa-4,4-diphenylbicyclo(3.3.0)octane, a novel chiral catalytic source containing the N-(C=NH)-O moiety, has been synthesized and successfully utilized, for the first time, as a chiral catalytic source in the borane-mediated asymmetric reduction of prochiral ketones in refluxing toluene, to provide the corresponding secondary alcohols with up to 93% enantiomeric excess. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：963 / 967

页数：5

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