Production of cephamycin C in repeated batch operations from immobilized Streptomyces clavuligerus

被引：19

作者：

Devi, S ^{[1
]}

Sridhar, P ^{[1
]}

机构：

[1] Osmania Univ, Dept Microbiol, Hyderabad 500007, Andhra Pradesh, India

来源：

PROCESS BIOCHEMISTRY | 2000年 / 36卷 / 03期

关键词：

Streptomyces clavuligerus; immobilized cells; cephamycin C production; alginate; sponge;

D O I：

10.1016/S0032-9592(00)00194-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Streptomyces clavuligerus cells were immobilized with two different supports - via sponge and 4% alginate; and cephamycin C production in repeated batch operations were estimated and compared. A gradual increase was observed in cephamycin C production from 48 to 96 h during fermentation. Sponge immobilized cells showed better production levels than alginate immobilized cells. Even in terms of operational considerations such as ease of preparation of immobilized cells, ease for repeated operations when compared, sponge was a better support material than alginate for immobilization. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：225 / 231

页数：7