Fiber optic sensor modified by graphene oxide-glucose oxidase for glucose detection

被引：22

作者：

Li Jia-xin ^{[1
]}

Zhang Wei-hua ^{[1
]}

Tong Zheng-rong ^{[1
]}

Liu Jing-wei ^{[1
]}

机构：

[1] Tianjin Univ Technol, Engn Res Ctr Optoelect Devices & Commun Technol, Sch Elect & Elect Engn, Tianjin Key Lab Film Elect & Commun Devices,Minis, Tianjin 300384, Peoples R China

来源：

OPTICS COMMUNICATIONS | 2021年 / 492卷

关键词：

Optic fiber sensor; Biosensors; Dual-parameter measurement; Glucose concentration; INTERFEROMETER;

D O I：

10.1016/j.optcom.2021.126983

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

A biosensor modified by graphene oxide (GO)-glucose oxidase (GOD) for glucose detection is proposed and demonstrated. Gluconic acid and H2O2 are produced by the reaction between GOD and glucose, and due to the large change of the refractive index (RI) around the sensor, the drift of the interference valleys appears in the transmission spectrum clearly. With this method, a symmetric lateral-offset sensor based on photonic crystal fiber (PCF) is fabricated. Response characteristics of glucose concentration are tested in the range of 10 g/L to 70 g/L. Experimental results show that the sensitivity to glucose concentration can be represented by a quadratic curve, and it has good sensitivity as well as linearity. The temperature sensitivities in the range of 5 degrees C-30 degrees C are 0.061 nm/degrees C and 0.159 nm/degrees C, which can realize dual-parameter measurement. The biosensor has broad application prospects in the fields of environmental detection and drug research.

引用

页数：6

共 17 条

[1] Chemical sensing using a polymer coated long-period fiber grating interrogated by ring-down spectroscopy [J].

Barnes, J. A. ;

Brown, R. S. ;

Cheung, A. H. ;

Dreher, M. A. ;

Mackey, G. ;

Loock, H. -P. .

SENSORS AND ACTUATORS B-CHEMICAL, 2010, 148 (01) :221-226

[2] Review of plasmonic fiber optic biochemical sensors: improving the limit of detection [J].

Caucheteur, Christophe ;

Guo, Tuan ;

Albert, Jacques .

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2015, 407 (14) :3883-3897

[3] Application of novel notched long-period fiber grating for glucose concentration measurement [J].

Chang, Yuan-Cheng ;

Wu, Janw-Wei ;

Chiang, Chia-Chin .

JAPANESE JOURNAL OF APPLIED PHYSICS, 2015, 54 (06)

[4] Graphene Oxide: Preparation, Functionalization, and Electrochemical Applications [J].

Chen, Da ;

Feng, Hongbin ;

Li, Jinghong .

CHEMICAL REVIEWS, 2012, 112 (11) :6027-6053

[5] Recent development in optical fiber biosensors [J].

Espinosa Bosch, Maria ;

Ruiz Sanchez, Antonio Jesus ;

Sanchez Rojas, Fuensanta ;

Bosch Ojeda, Catalina .

SENSORS, 2007, 7 (06) :797-859

[6] Acute ischemic stroke and abnormal blood hemoglobin concentration [J].

Furlan, J. C. ;

Fang, J. ;

Silver, F. L. .

ACTA NEUROLOGICA SCANDINAVICA, 2016, 134 (02) :123-130

[7] Highly Sensitive Plasmonic Sensor Based on Ring Shape Nanoparticles for the Detection of Ethanol and D-Glucose Concentration [J].

Heidarzadeh, Hamid .

IEEE TRANSACTIONS ON NANOTECHNOLOGY, 2020, 19 :397-404

[8] High-sensitivity DNA biosensor based on optical fiber taper interferometer coated with conjugated polymer tentacle [J].

Huang, Yunyun ;

Tian, Zhuang ;

Sun, Li-Peng ;

Sun, Dandan ;

Li, Jie ;

Ran, Yang ;

Guan, Bai-Ou .

OPTICS EXPRESS, 2015, 23 (21) :26962-26968

[9] Label-free glucose biosensor based on enzymatic graphene oxide-functionalized tilted fiber grating [J].

Jiang, Biqiang ;

Zhou, Kaiming ;

Wang, Changle ;

Sun, Qizhen ;

Yin, Guolu ;

Tai, Zhijun ;

Wilson, Karen ;

Zhao, Jianlin ;

Zhang, Lin .

SENSORS AND ACTUATORS B-CHEMICAL, 2018, 254 :1033-1039

[10] Dumbbell shaped inline Mach-Zehnder interferometer for glucose detection [J].

Lokman, A. ;

Arof, H. ;

Harun, S. W. .

MEASUREMENT, 2015, 59 :167-170

← 1 2 →