Barkhof Magnetic Resonance Imaging Criteria Predict Early Relapse in Pediatric Multiple Sclerosis

被引：8

作者：

Neuteboom, Rinze F.

Ketelslegers, Immy A.

Boon, Maartje ^{[2
]}

Catsman-Berrevoets, Coriene E.

Hintzen, Rogier Q. ^{[1
]}

机构：

[1] Sophia Childrens Univ Hosp, Erasmus Med Ctr, Multiple Sclerosis Ctr ErasMS, Dept Neurol, NL-3000 CA Rotterdam, Netherlands

[2] Univ Groningen Hosp, Dept Pediat Neurol, Groningen, Netherlands

来源：

PEDIATRIC NEUROLOGY | 2010年 / 42卷 / 01期

关键词：

EARLY-ONSET MS; PROGNOSTIC-FACTORS; CHILDHOOD; DEMYELINATION;

D O I：

10.1016/j.pediatrneurol.2009.07.013

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We sought to identify clinical and radiologic features predicting early relapse after a diagnosis of multiple sclerosis in children. In this nationwide retrospective multicenter study in The Netherlands, we included 28 children with multiple sclerosis with onset before age 16 years. Magnetic resonance images and clinical features at the onset of disease were evaluated. The mean follow-up time was 55 months. Twenty children (71%) had a relapse during follow-up. We found that the presence of at least three of four Barkhof magnetic resonance imaging criteria at the onset of multiple sclerosis signs is predictive of early relapse after a diagnosis of multiple sclerosis in children (P < 0.05). (C) 2010 by Elsevier Inc. All rights reserved.

引用

页码：53 / 55

页数：3

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