Combined Treatment With 131I-MIBG and Sunitinib Induces Remission in a Patient With Metastatic Paraganglioma Due to Hereditary Paraganglioma-Pheochromocytoma Syndrome From an SDHB Mutation

被引：8

作者：

Makis, William ^{[1
]}

McCann, Karey ^{[1
]}

McEwan, Alexander J. B. ^{[1
]}

Sawyer, Michael B. ^{[2
]}

机构：

[1] Cross Canc Inst, Dept Diagnost Imaging, 11560 Univ Ave NW, Edmonton, AB T6G 1Z2, Canada

[2] Cross Canc Inst, Dept Med Oncol, Edmonton, AB T6G 1Z2, Canada

来源：

CLINICAL NUCLEAR MEDICINE | 2016年 / 41卷 / 03期

关键词：

sunitinib; pheochromocytoma; paraganglioma; I-131-MIBG; THERAPY;

D O I：

10.1097/RLU.0000000000000973

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

A 22-year-old woman with rapidly progressing metastatic paraganglioma due to hereditary paraganglioma-pheochromocytoma syndrome from an SDHB mutation, who recurred after neoadjuvant chemotherapy, was found to be MIBG avid. She was treated with 2 I-131-MIBG treatments and concurrent sunitinib, achieving a complete response. She was in full remission for 9 months before developing bone metastases.

引用

页码：204 / 206

页数：3

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