Micropower fully integrated CMOS readout interface for neural recording application

In this paper, we presented a micropower, small-size fully integrated CMOS readout interface for neural recording system. A crucial and important module of this system is the amplifier circuit with low-power low-noise. We describe a micropower low-noise readout circuit using an active feedback fully differential structure to reject the 1/f noise and large DC-offsets. the substrate-bias technology to further decrease the noise and power of the neural recording amplifier. Therefore, the neural amplifier with micropower low-noise and high input impedance is presented. The readout interface core, fully differential amplifier is implemented in 0.35-mu m CMOS process, passes neural signals from 10 Hz to 9 kHz with an input-referred noise of 4.3 mu V-rms. The power consumption of single amplifier is 5.6 mu W while consuming 0.03 mm(2) of die area. The low cutoff frequencies of the circuit can adjusted from 10 Hz to 400 Hz, and the high cutoff frequencies form 4 kHz to 9 kHz. (C) 2009 Elsevier Ltd. All rights reserved.